Spin-label and fluorescence labeling studies of the thioester bonds in human .alpha.2-macroglobulin

The interaction of α2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

1973 • 1,062 citations

Synthesis and spectral properties of a hydrophobic fluorescent probe: 6-propionyl-2-(dimethylamino)naphthalene

1979 • 811 citations

STUDIES ON HUMAN PLASMA α2-MACROGLOBULIN-ENZYME INTERACTIONS

1973 • 362 citations

Lanthanides as probes for calcium in biological systems

1979 • 362 citations

A thiol‐ester in α₂‐macroglobulin cleaved during proteinase complex formation

1980 • 330 citations

A novel reversible thiol-specific spin label: Papain active site labeling and inhibition

1982 • 303 citations

Primary structure of human alpha 2-macroglobulin. V. The complete structure.

1984 • 253 citations

Physical and chemical properties of human plasma β2-macroglobulin

1978 • 244 citations

Purification of human plasma α2 macroglobulin and α1 proteinase inhibitor using zinc chelate chromatography

1979 • 213 citations

Structural characterization of human alpha2-macroglobulin subunits.

1979 • 207 citations

Thiol reduction of human α2-macroglobulin. The subunit structure

1972 • 149 citations

Model of alpha 2-macroglobulin structure and function.

1985 • 138 citations

Mechanism of .alpha.2-macroglobulin-proteinase interactions. Studies with trypsin and plasmin

1984 • 76 citations

Effects of Solvents on Fluorescence Emission Spectra

1983 • 67 citations

Relation of internal thioesters to conformational change and receptor-recognition site in α2-macroglobulin complexes

1982 • 67 citations

The Combining Ratio between Trypsin and Serum alpha2-Macroglobulin.

1966 • 65 citations

Localization of the two protease binding sites in human alpha 2-macroglobulin.

1981 • 59 citations

THE SPIN‐LABEL APPROACH TO LABELING MEMBRANE PROTEIN SULFHYDRYL GROUPS*

1983 • 57 citations

Reaction of purified (Na,K)-ATPase with the fluorescent sulfhydryl probe 2-(4'-maleimidylanilino)naphthalene 6-sulfonic acid. Characterization and the effects of ligands.

1979 • 51 citations

Thrombin-induced conformational changes of human .alpha.2-macroglobulin: evidence for two functional domains

1985 • 50 citations

Structural changes in alpha-2- and ovomacroglobulins studied by gel chromatography and electron microscopy

1985 • 46 citations

Proximity of thiol esters and bait region in human .alpha.2 macroglobulin: paramagnetic mapping

1988 • 44 citations

Fluorescent affinity labeling of initiation site on ribonucleic acid polymerase of Escherichia coli

1974 • 42 citations

Kinetics of appearance of sulfhydryl groups in .alpha.2-macroglobulin on reaction of the inhibitor with amines

1984 • 36 citations

α₂‐MACROGLOBULIN: AN INTRODUCTION

1983 • 36 citations

The conformational changes of α2-macroglobulin induced by methylamine or trypsin. Characterization by extrinsic and intrinsic spectroscopic probes

1987 • 28 citations

Reaction of methylamine with human alpha 2-macroglobulin. Mechanism of inactivation.

1985 • 26 citations

STRUCTURE OF α₂‐MACROGLOBULIN IN SOLUTION AND ITS INTERACTION WITH PROTEASES: AN X‐RAY SCATTERING STUDY USING THE CONTRAST VARIATION METHOD

1983 • 24 citations

In support of the trap hypothesis. Chymotrypsin is not rigidly held in its complex with human .alpha.2-macroglobulin

1987 • 23 citations

Temperature and pH dependence of the association rate constant of elastase with alpha 2-macroglobulin.

1984 • 19 citations

Kinetics of conformational changes and inactivation of human .alpha.2-macroglobulin on reaction with methylamine

1985 • 16 citations

Localization of the proteinase-induced thiol groups in α2-macroglobulin

1983 • 10 citations

Specific fluorescent labeling of α2-macroglobulin-bound proteases: accessibility and localization of their active site within the complex

1986 • 5 citations

Selective action of α2-macroglobulin-plasmin complex on fibrin

1981 • 5 citations

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