ADVERSE EFFECTS OF OPIOID ANALGESIC DRUGS

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

A CLINICAL METHOD FOR ASSESSING THE VENTILATORY RESPONSE TO CARBON DIOXIDE

1967 • 1,147 citations

Multiple opiate receptor sites on primary afferent fibres

1980 • 621 citations

Cardiovascular Effects of Endogenous Opiate Systems

1983 • 567 citations

Central nervous system excitatory effects of meperidine in cancer patients

1983 • 409 citations

Buprenorphine

1979 • 400 citations

Electrophysiology of opioids.

1983 • 377 citations

NAUSEA AND VOMITING

1984 • 352 citations

Histamine Release during Morphine and Fentanyl Anesthesia

1982 • 309 citations

Anesthetic Requirements and Cardiovascular Effects of Fentanyl-Oxygen and Fentanyl-Diazepam-Oxygen Anesthesia in Man

1978 • 292 citations

NARCOTIC ANALGESICS AND DELAYED GASTRIC EMPTYING DURING LABOUR

1975 • 284 citations

Inhibition of gastric emptying and drug absorption by narcotic analgesics.

1975 • 270 citations

Patient-controlled Analgesic Therapy, Part IV

1982 • 264 citations

Effect of Carotid Endarterectomy on Carotid Chemoreceptor and Baroreceptor Function in Man

1970 • 260 citations

Ceiling effect for respiratory depression by nalbuphine

1980 • 248 citations

Pain as a major cause of postoperative nausea

1976 • 244 citations

Multiple intramuscular injections: A major source of variability in analgesic response to meperidine

1980 • 220 citations

Relationship Between Blood Meperidine Concentrations and Analgesic Response

1980 • 207 citations

Plasma Catecholamine and Cortisol Responses to Fentanyl–Oxygen Anesthesia for Coronary-artery Operations

1980 • 199 citations

ENDOCRINE AND METABOLIC CHANGES DURING SURGERY: ANAESTHETIC IMPLICATIONS

1981 • 192 citations

Comparison of Histamine Release in Human Skin Mast Cells Induced by Morphine, Fentanyl, and Oxymorphone

1985 • 149 citations

THE LOWER OESOPHAGEAL SPHINCTER AND ANAESTHESIA

1984 • 137 citations

Physiology of Alfentanil-induced Rigidity

1986 • 135 citations

Substrate mobilisation during surgery

1978 • 129 citations

Drug-Induced Agranulocytosis

1978 • 128 citations

Sudden Death following Naloxone Administration

1981 • 127 citations

Prolonged Antagonism of Opioid Action with Intravenous Nalmefene in Man

1986 • 120 citations

The effects of premedication drugs on the lower oesophageal high pressure zone and reflux status of rhesus monkeys and man.

1975 • 116 citations

A study of some of the pharmacologic actions of fentanyl citrate

1964 • 113 citations

Unexpected complication of successful nerve block

1981 • 112 citations

ELECTROENCEPHALOGRAPHIC EFFECTS OF SUFENTANIL ANAESTHESIA IN MAN

1982 • 107 citations

Delayed respiratory depression after use of fentanyl during anaesthesia.

1978 • 106 citations

Butorphanol

1978 • 103 citations

Acute Pulmonary Edema in Healthy Teenagers Following Conservative Doses of Intravenous Naloxone

1984 • 100 citations

The interaction between monoamine oxidase inhibitors and narcotic analgesics in mice

1969 • 97 citations

Abdominal-muscle Rigidity Induced by Morphine and Nitrous Oxide

1973 • 97 citations

Seizure-like Movements during a Fentanyl Infusion with Absence of Seizure Activity in a Simulataneous EEG Recording

1985 • 95 citations

The action of sennosides and related compounds on human colon and rectum

1970 • 92 citations

Hypertensive Reaction to Naloxone

1974 • 86 citations

A Pharmacokinetic Approach to Postoperative Pain: Continuous Infusion of Pethidine

1979 • 86 citations

POSTANESTHETIC NAUSEA AND VOMITING

1961 • 85 citations

INHIBITION OF VASOPRESSIN RELEASE IN MAN BY AN OPIATE PEPTIDE

1980 • 83 citations

Plasma Antidiuretic Hormone Levels in Cardiac Surgical Patients during Morphine and Halothane Anesthesia

1978 • 81 citations

Relief of pain by infusion of morphine after operation: does tolerance develop?

1985 • 76 citations

PLASMA FENTANYL CONCENTRATIONS AND CLINICAL OBSERVATIONS DURING AND AFTER OPERATION

1979 • 75 citations

The Clinical Pharmacology of Meperidine—Comparison of Routes of Administration

1976 • 74 citations

Neurotoxicity of meperidine

1985 • 73 citations

Naloxone and morphine inhibit gastric emptying of solids

1982 • 72 citations

The effects of prior fentanyl administration and of pain on fentanyl analgesia: tolerance to and enhancement of narcotic analgesia.

1980 • 71 citations

The Effects of Drugs and Anaesthetic Agents on the Urinary Bladder and Sphincters

1976 • 69 citations

GASTRIC EMPTYING FOLLOWING HYSTERECTOMY WITH EXTRADURAL ANALGESIA

1978 • 65 citations

Dynamics of acute retention in prostatic patient and role of adrenergic receptors

1977 • 64 citations

EFFECT OF PHYSOSTIGMINE ON MORPHINE-INDUCED POSTOPERATIVE PAIN AND SOMNOLENCE

1982 • 61 citations

Spinal opiates affect sexual behaviour in rats

1984 • 61 citations

Intraspinal opiates and itching: a new reflex?

1982 • 59 citations

Cardiac arrest after reversal of effects of opiates with naloxone.

1984 • 59 citations

Effects of Butorphanol, Nalbuphine, and Fentanyl on Intrabiliary Tract Dynamics

1984 • 58 citations

New and Experimental Therapeutic Roles for Naloxone and Related Opioid Antagonists

1984 • 58 citations

Morphine Decreases Peripheral Vascular Resistance and Increases Capacitance in Man

1979 • 57 citations

ELEVATION OF PLASMA HISTAMINE LEVELS IN THE DOG FOLLOWING ADMINISTRATION OF MUSCLE RELAXANTS, OPIATES AND MACROMOLECULAR POLYMERS.

1964 • 54 citations

URINARY RETENTION DURING I.M. AND EXTRADURAL MORPHINE ANALGESIA

1982 • 54 citations

VENTILATORY EFFECTS AND PLASMA CONCENTRATION OF MORPHINE IN MAN

1978 • 52 citations

Local and neurally mediated effects of morphine on skeletal muscle vascular resistance.

1972 • 52 citations

Postoperative Rigidity Following Fentanyl Anesthesia

1983 • 51 citations

Choreic Movements Induced by the Use of Methadone

1980 • 51 citations

Physostigmine Antagonizes Morphine-induced Respiratory Depression in Human Subjects

1983 • 50 citations

METHADONE INDUCED HYPOADRENALISM

1982 • 49 citations

Thrombocytopenia and Intravenous Heroin Use

1978 • 47 citations

Low-dose fentanyl: Haemodynamic response during induction and intubation in geriatric patients

1985 • 45 citations

Systemic availability of orally administered meperidine

1976 • 44 citations

THE ROLE OF THE VESTIBULAR APPARATUS IN THE PRODUCTION OF NAUSEA AND VOMITING FOLLOWING THE ADMINISTRATION OF MORPHINE TO MAN

1950 • 44 citations

Direct Opioid Application to Peripheral Nerves Does Not Alter Compound Action Potentials

1985 • 43 citations

Opioid analgesics and narcotic antagonists

2012 • 43 citations

A DOUBLE-BLEND CONTROLLED STUDY OF THE EFFECTS ON RESPIRATION OF PENTAZOCINE, PHENOPERIDINE AND MORPHINE IN NORMAL MAN

1968 • 42 citations

Liver damage from narcotics in mice

1981 • 39 citations

Postoperative Rigidity Following Sufentanil Administration

1985 • 39 citations

Hemodynamic and Catecholamine Changes after Administration of Naloxone

1982 • 38 citations

Gangrene of the upper extremity following intra-arterial injection of drugs. A case report and review of the literature.

1984 • 38 citations

The respiratory and subjective effects of pentazocine

1965 • 37 citations

Drug utilization in a general intensive care unit

1978 • 37 citations

Cardio‐Respiratory Toxicity of Propoxyphene and Norpropoxyphene in Conscious Rabbits*

1978 • 36 citations

Pigmented lesions of the tongue in heroin addicts—fixed drug eruption

1983 • 36 citations

Medicines Evaluation and Monitoring Group: Central Nervous System Effects of Pentazocine

1974 • 36 citations

Incidence of Choledochoduodenal Sphincter Spasm during Fentanyl-Supplemented Anesthesia

1982 • 35 citations

Antisecretory activity of opiates in vitro and in vivo in man.

1983 • 33 citations

Severe Hypertension Induced by Naloxone

1985 • 31 citations

Hepatic injury induced by anesthetic agents in rats.

1983 • 31 citations

VARIATION IN THE DISPOSITION OF MORPHINE AFTER I.M. ADMINISTRATION IN SURGICAL PATIENTS

1978 • 29 citations

COMPARISON OF EFFECTS OF INTRAOPERATIVE AND POSTOPERATIVE METHADONE: ACUTE TOLERANCE TO THE POSTOPERATIVE DOSE?

1983 • 27 citations

Narcotic-induced choledochoduodenal sphincter spasm reversed by glucagon.

1980 • 26 citations

Pethidine, metoclopramide and the gastro‐oesophageal sphincter

1981 • 26 citations

Muscle fibrosis and contractures in a pethidine addict.

1971 • 25 citations

Influence of Fentanyl and Morphine on Intestinal Circulation

1985 • 25 citations

POST-OPERATIVE VOMITING

1934 • 25 citations

Studies of analgesic drugs. X. Respiratory effects of narcotic antagonists.

1966 • 24 citations

Acute urinary retention associated with sublingual buprenorphine.

1983 • 22 citations

Prevention of urinary retention with phenoxybenzamine during epidural morphine.

1984 • 20 citations

Morphine-Induced Respiratory Depression following Bilateral Carotid Endarterectomy

1981 • 20 citations

Opposite Effects on Human Distal Colon Motility of Two Postulated Alpha₂‐Antagonists (Mianserin and Chlorprothixene) and One Alpha₂‐Agonist (Clonidine)

1983 • 18 citations

Respiratory depression after alfentanil infusion.

1984 • 16 citations

PENTAZOCINE IN SEQUENTIAL ANALGESIC ANAESTHESIA

1972 • 16 citations

The reversal of epidural morphine induced somnolence with physostigmine

1984 • 16 citations

Telogen Effluvium after Anesthesia and Surgery

1984 • 15 citations

Naloxone Reversal of Morphine-Induced Biliary Colic

1981 • 14 citations

Neuroleptanaesthesia for surgery of the abdominal aorta

1978 • 14 citations

Fibrous myopathy in association with pentazocine.

1983 • 13 citations

Respiratory Depression after Epidural Morphine in the Postoperative Period. Influence of Posture

1984 • 10 citations

EFFECT OF A NEW ANALEPTIC DRUG, ALMITRINE, ON FENTANYL-INDUCED RESPIRATORY DEPRESSION AND ANALGESIA IN MAN

1982 • 10 citations

Morphine-Induced Immune Thrombocytopenia

1982 • 9 citations

Effects of Volatile Anesthetics or Fentanyl on Hepatic Function in Cirrhotic Rats

1986 • 8 citations

Narcotics and spasm of the sphincter of Oddi. A retrospective study of operative cholangiograms

1983 • 7 citations

Epidural Fentanyl Counteracts Sympathetic Gastric Inhibition

1985 • 6 citations

Intermittent Heart Block Related to Treatment of Hypertension in a Patient with Acute Myocardial Infarction

1972 • 6 citations

An update on opioid receptors.

1983 • 6 citations

The effect of naloxone on the preoperative gastric volume and pH

1986 • 3 citations

Hemolysis after administration of high-dose fentanyl.

1986 • 3 citations

LIMITED ENTERO-SYSTEMIC RECIRCULATION AFTER GASTRIC TRAPPING OF FENTANYL IN THE DOG

1985 • 1 citations