Second Messenger Signaling in the Regulation of Collagenase Production by Osteogenic Sarcoma Cells*

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

The Calcium Messenger System

1986 • 669 citations

Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption.

1987 • 539 citations

The Effect of Calcium-Regulating Hormones and Prostaglandins on Bone Resorption by Osteoclasts Disaggregated from Neonatal Rabbit Bones*

1985 • 419 citations

Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

1985 • 415 citations

Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts.

1986 • 392 citations

The Effect of Parathyroid Hormone on the Concentration of Adenosine 3',5'-Monophosphate in Skeletal Tissue in Vitro

1970 • 319 citations

Osteoblast-Like Cells in the Presence of Parathyroid Hormone Release Soluble Factor that Stimulates Osteoclastic Bone Resorption*

1986 • 317 citations

Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin.

1983 • 310 citations

Parathyroid hormone-activated calcium channels in an osteoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels.

1987 • 283 citations

Functional Properties of Hormonally Responsive Cultured Normal and Malignant Rat Osteoblastic Cells*

1981 • 278 citations

Effects of vitamin D3 metabolites on cytosolic free calcium in confluent mouse osteoblasts.

1987 • 246 citations

Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.

1985 • 239 citations

Stimulation of inositol trisphosphate and diacylglycerol production in renal tubular cells by parathyroid hormone.

1987 • 232 citations

Bone cells predispose bone surfaces to resorption by exposure of mineral to osteoclastic contact

1985 • 229 citations

1,25-Dihydroxyvitamin D3 stimulates rat osteoblastic cells to release a soluble factor that increases osteoclastic bone resorption.

1987 • 218 citations

Hormonal Control of Bone Collagen Synthesisin Vitro: Effects of Parathyroid Hormone and Calcitonin

1976 • 214 citations

Parathyroid hormone receptor in intact embryonic chicken bone: characterization and cellular localization.

1982 • 209 citations

Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.

1986 • 198 citations

Mouse osteoblasts synthesize collagenase in response to bone resorbing agents

1984 • 192 citations

Characterization of an osteoblast-like clonal cell line which responds to both parathyroid hormone and calcitonin

1985 • 188 citations

Hormonal Regulation of the Production of Collagenase and a Collagenase Inhibitor Activity by Rat Osteogenic Sarcoma Cells*

1987 • 186 citations

A two-receptor model for the action of parathyroid hormone on osteoblasts: A role for intracellular free calcium and cAMP

1985 • 177 citations

Regulation of Plasminogen Activator Production by Bone-Resorbing Hormones in Normal and Malignant Osteoblasts*

1985 • 151 citations

Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells

1987 • 148 citations

Activation of Adenosine 3',5'-Monophosphate-Dependent Protein Kinase in Normal and Malignant Bone Cells by Parathyroid Hormone, Prostaglandin E₂, and Prostacyclin*

1981 • 143 citations

Synthesis of collagenase and collagenase inhibitors by osteoblast-like cells in culture

1984 • 125 citations

Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line.

1985 • 125 citations

Effects of parathyroid hormone on cytosolic calcium in renal proximal tubular primary cultures

1986 • 105 citations

Stimulation of plasminogen activator in osteoblast-like cells by bone-resorbing hormones

1984 • 95 citations

Relationship between phospholipase C activation and prostaglandin E2 and cyclic adenosine monophosphate production in rabbit tubular epithelial cells. Effects of angiotensin, bradykinin, and arginine vasopressin.

1988 • 58 citations

<b>IMMUNOCYTOCHEMICAL LOCALIZATION OF COLLAGENASE IN ISOLATED MOUSE BONE </b><b>CELLS </b>

1984 • 58 citations

Collagenase production by smooth muscle: Correlation of immunoreactive with functional enzyme in the myometrium

1986 • 45 citations

12-O-Tetradecanoyl Phorbol-13-Acetate Potentiates Adenosine 3′,5′-Monophosphate-Mediated Chorionic Gonadotropin Secretion by Cultured Human Choriocarcinoma Cells*

1987 • 33 citations

Activation of cyclic adenosine 3':5'-monophosphate-dependent protein kinase in H35 hepatoma and Chinese hamster ovary cells by a phorbol ester tumor promoter.

1983 • 28 citations

PTH (parathyroid hormone) elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line

1988 • 22 citations

Monensin inhibits collagenase production in osteoblastic cell cultures and also inhibits both collagenase release and bone resorption in mouse calvaria cultures.

1985 • 11 citations