Increased gene expression of neuronal nitric oxide synthase in brain of adult spontaneously hypertensive rats

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei

1983 • 1,962 citations

Nitric oxide, a novel neuronal messenger

1992 • 1,864 citations

Histochemical mapping of nitric oxide synthase in the rat brain

1992 • 1,858 citations

The paraventricular nucleus of the hypothalamus: Cytoarchitectonic subdivisions and organization of projections to the pituitary, dorsal vagal complex, and spinal cord as demonstrated by retrograde fluorescence double‐labeling methods

1980 • 1,391 citations

Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat

1978 • 1,344 citations

Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat

1982 • 1,149 citations

A Complete Protocol forIn SituHybridization of Messenger RNAs in Brain and Other Tissues With Radio-labeled Single-Stranded RNA Probes

1989 • 883 citations

Nitric Oxide and Synaptic Function

1994 • 779 citations

Afferent connections to the sensory trigeminal nuclei, the nucleus of the solitary tract and adjacent structures. An experimental study in the rat

1956 • 754 citations

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase

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Sympathetic nerve activity: role in regulation of blood pressure in the spontaenously hypertensive rat.

1976 • 429 citations

Function of the ventrolateral medulla in the control of the circulation

1986 • 334 citations

Distribution of reduced‐nicotinamide‐adenine‐dinucleotide‐phosphate diaphorase‐positive cells and fibers in the cat central nervous system

1989 • 278 citations

Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits.

1993 • 275 citations

Cardiovascular Effects of Nitric Oxide in the Brain Stem Nuclei of Rats

1996 • 258 citations

Up-regulation of nitric oxide synthase (NOS) gene expression together with NOS activity in the rat hypothalamo-hypophysial system after chronic salt loading: evidence of a neuromodulatory role of nitric oxide in arginine vasopressin and oxytocin secretion.

1994 • 245 citations

Pathophysiology of renovascular hypertension.

1991 • 223 citations

Chapter 12 Regulation of multiple peptides in CRF parvocellular neurosecretory neurons: implications for the stress response

1986 • 220 citations

Nitric oxide actions in paraventricular nucleus: cardiovascular and neurochemical implications

1994 • 197 citations

Nitric oxide synthase immunoreactivity in rat pontine medullary neurons

1994 • 196 citations

Vasopressin in the rat with spontaneous hypertension

1978 • 181 citations

Nitric oxide influences ventrolateral medullary mechanisms of vasomotor control in the cat

1991 • 172 citations

Stress-induced activation of nitric oxide-producing neurons in the rat brain

1997 • 170 citations

Inhibition of basal and reflex-mediated sympathetic activity in the RVLM by nitric oxide

1995 • 155 citations

Chapter 4 Central control of the circulation by the rostral ventrolateral reticular nucleus: anatomical substrates

1989 • 143 citations

Sympathetic nerve activity and blood pressure in normotensive backcross rats genetically related to the spontaneously hypertensive rat.

1979 • 142 citations

Nitric oxide synthase increases in hypothalamic magnocellular neurons after salt loading in the rat. An immunohistochemical and in situ hybridization study

1994 • 138 citations

Renal sympathetic activity in spontaneously hypertensive rats and normotensive controls, as studied by three different methods

1984 • 136 citations

Immobilization-induced stress activates neuronal nitric oxide synthase (nNOS) mRNA and protein in hypothalamic-pituitary-adrenal axis in rats

1996 • 134 citations

Central inhibition of nitric oxide synthase preferentially augments release of oxytocin during dehydration

1993 • 124 citations

Sympathetic Discharge Rate in Spontaneously Hypertensive Rats

1973 • 122 citations

Decreased gene expression of neuronal nitric oxide synthase in hypothalamus and brainstem of rats in heart failure

1996 • 105 citations

Mieroinjection of S-nitrosocysteine into the nucleus tractus solitarii decreases arterial pressure and heart rate via activation of soluble guanylate cyclase

1991 • 102 citations

Hypertensive strains and normotensive 'control' strains. How closely are they related?

1992 • 101 citations

Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats.

1993 • 98 citations

Up-regulation of nitric oxide synthase (NOS) gene expression together with NOS activity in the rat hypothalamo-hypophysial system after chronic salt loading: evidence of a neuromodulatory role of nitric oxide in arginine vasopressin and oxytocin secretion

1994 • 90 citations

Role of sympathetic nerve activity in the generation of vascular nitric oxide in urethane-anesthetized rats.

1991 • 88 citations

A morphometric analysis of functionally defined subpopulations of neurons in the paraventricular nucleus of the rat with observations on the effects of colchicine

1989 • 79 citations

Genetic divergence between the Wistar-Kyoto rat and the spontaneously hypertensive rat.

1992 • 69 citations

Activation by hypotension of neurons in the hypothalamic paraventricular nucleus that project to the brainstem

1997 • 66 citations

L-Glutamate Evokes the Release of an Endothelium-Derived Relaxing Factor-Like Substance from the Rat Nucleus Tractus Solitarius

1991 • 65 citations

Evidence for a critical role of nitric oxide in the tonic excitation of rabbit renal sympathetic preganglionic neurones.

1995 • 54 citations

Neurons in the rat medulla oblongata containing neuropeptide Y-, angiotensin II-, or galanin-like immunoreactivity project to the parabrachial nucleus

1992 • 51 citations

Changes in paraventricular vasopressin and oxytocin during the development of spontaneous hypertension.

1983 • 50 citations

Gene Expression of Brain Nitric Oxide Synthase and Soluble Guanylyl Cyclase in Hypothalamus and Medulla of Two-Kidney, One Clip Hypertensive Rats

1995 • 50 citations

Hypotension induces fos immunoreactivity in NADPH-diaphorase positive neurons in the paraventricular and supraoptic hypothalamic nuclei of the rat

1995 • 42 citations

Nitric oxide reduces body temperature and sympathetic input to brown adipose tissue during PGE1-hyperthermia

1995 • 38 citations

Inhibition of NO synthase in the posterior hypothalamus increases blood pressure in the rat.

1995 • 33 citations

Brain nitric oxide synthase activity in normal, hypertensive, and stroke-prone rats.

1994 • 32 citations

Calcium-activated release of nitric oxide potentiates excitatory synaptic potentials in immature rat sympathetic preganglionic neurons

1995 • 32 citations

Renal nerve activity in rats with spontaneous hypertension: effect of converting enzyme inhibitor

1992 • 27 citations