Phorbol myristate acetate (PMA) suppresses polarization and locomotion and alters F‐actin content of walker carcinosarcoma cells

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: Part 1

1980 • 477 citations

Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity

1975 • 413 citations

Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets.

1985 • 308 citations

A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells.

1984 • 303 citations

Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.

1985 • 234 citations

Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.

1984 • 221 citations

Cyclic GMP and Cell Movement

1973 • 218 citations

Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium

1983 • 217 citations

Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.

1985 • 203 citations

Role of secretory events in modulating human neutrophil chemotaxis.

1978 • 193 citations

Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.

1984 • 193 citations

Chemotactic peptide-induced changes in neutrophil actin conformation.

1984 • 186 citations

Action of phorbol esters in cell culture: Mimicry of transformation, altered differentiation, and effects on cell membranes

1979 • 181 citations

Cyclic AMP, the microtubule-microfilament system, and cancer.

1977 • 170 citations

Effects of phorbol-12,13-diesters on prostaglandin production and phospholipase activity in canine kidney (MDCK) cells

1977 • 155 citations

Changes in cytoskeletal proteins of polymorphonuclear leukocytes induced by chemotactic peptides

1983 • 153 citations

Motility and adhesive properties of high- and low-metastatic murine neoplastic cells.

1984 • 148 citations

Diacylglycerol in large α-actinin/actin complexes and in the cytoskeleton of activated platelets

1985 • 147 citations

Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.

1985 • 140 citations

The Pharmacology of Inflammation

1986 • 121 citations

Human Neutrophil Heterogeneity Identified Using Flow Microfluorometry to Monitor Membrane Potential

1981 • 96 citations

Ca2+-Activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins

1984 • 91 citations

Membrane Potential Changes During Chemokinesis in Paramecium

1979 • 89 citations

Actin cytoskeletal organization loss in the benign-to-malignant tumor transition in cultured human colonic epithelial cells.

1984 • 83 citations

Studies on the regulation of the neutrophil chemotactic response using a rapid and reliable method for measuring random migration and chemotaxis of neutrophil granulocytes

1976 • 79 citations

Themotaxis of metastatic tumor cells

1982 • 67 citations

Crawling-like movements, adhesion to solid substrata and chemokinesis of neutrophil granulocytes

1983 • 60 citations

Motility, cell shape, and locomotion of neutrophil granulocytes

1983 • 56 citations

Centripetal myosin redistribution in thrombin-stimulated platelets

1984 • 44 citations

Shape changes and chemokinesis of Walker 256 carcinosarcoma cells in response to colchicine, vinblastine, nocodazole and taxol.

1986 • 40 citations

Increased fluorescence polarization of 1,6‐diphenyl‐1,3,5‐hexatriene in the phorbol myristate acetate‐stimulated plasma membrane of human neutrophils

1982 • 29 citations

Phorbol myristate acetate-induced adherence of Walker 256 carcinosarcoma cells.

1982 • 26 citations

Intracellular calcium redistribution and its relationship to fMet‐Leu‐Phe, leukotriene B₄, and phorbol ester induced rabbit neutrophil degranulation

1985 • 23 citations

Phosphorylation of myosin light chain in intact pig leukocytes stimulated by phorbol 12-myristate 13-acetate

1984 • 17 citations

Relationships between chemotaxis, chemotactic modulators, and cyclic nucleotide levels in tumor cells.

1983 • 14 citations

Functional Responses of Tumor Cells to Phorbol Esters: Role for Prostaglandins

1984 • 13 citations

Phorbol ester binding to chemotactically responding and nonresponding Walker 256 carcinosarcoma cells.

1984 • 9 citations

Shape and Motility of Leukocytes and Tumor Cells

2015 • 4 citations

Chemotaxis of Tumor Cells

1983 • 1 citations