Extracellular Domains of the Bradykinin B2 Receptor Involved in Ligand Binding and Agonist Sensing Defined by Anti-peptide Antibodies

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Enzyme-linked immunosorbent assay (ELISA) quantitative assay of immunoglobulin G

1971 • 3,630 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

Bioregulation of kinins: kallikreins, kininogens, and kininases.

1992 • 1,732 citations

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

1993 • 1,213 citations

Hoe 140 a new potent and long acting bradykinin‐antagonist: in vivo studies

1991 • 841 citations

Chimeric α ₂ -,β ₂ -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity

1988 • 766 citations

The Isolation and Properties of a Rabbit Liver Binding Protein Specific for Asialoglycoproteins

1974 • 614 citations

Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor

1992 • 472 citations

New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates

1979 • 463 citations

Expression cloning of a human B1 bradykinin receptor.

1994 • 455 citations

Expression cloning of a rat B2 bradykinin receptor.

1991 • 430 citations

Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2.

1987 • 375 citations

Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta 1-adrenoceptor with positive chronotropic effect.

1994 • 348 citations

Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors.

1993 • 321 citations

Antibodies to the alpha q subfamily of guanine nucleotide-binding regulatory protein alpha subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones.

1991 • 320 citations

Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy.

1993 • 267 citations

Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors

1993 • 206 citations

Functional autoimmune epitope on α1-adrenergic receptors in patients with malignant hypertension

1994 • 121 citations

Probing for the bradykinin B2 receptor in rat kidney by anti-peptide and anti-ligand antibodies.

1995 • 115 citations

Receptors for bradykinin in intact cultured human fibroblasts. Identification and characterization by direct binding study.

1983 • 78 citations

A Proposed Model of Bradykinin Bound to the Rat B2 Receptor and Its Utility for Drug Design

1994 • 76 citations

Structural features of the human bradykinin B2 receptor probed by agonists, antagonists, and anti-idiotypic antibodies

1993 • 67 citations

Bradykinin Induces Translocation of the Protein Kinase C Isoforms α, ɛ, and ζ

1994 • 61 citations

Delineation of a region in the B2 bradykinin receptor that is essential for high-affinity agonist binding.

1994 • 61 citations

Recent Progress on Kinins

1992 • 56 citations

Human β₂‐adrenergic receptor produced in stably transformed insect cells is functionally coupled via endogenous GTP‐binding protein to adenylyl cyclase

1993 • 48 citations

Stepping up the pressure

1992 • 47 citations

Mutation of Aspartate Residues in the Third Extracellular Loop of the Rat B2 Bradykinin Receptor Decreases Affinity for Bradykinin

1994 • 37 citations

[19] Kinin receptors

1988 • 30 citations

Anti-idiotypic antibodies bearing the internal image of a bradykinin epitope. Production, characterization, and interaction with the kinin receptor.

1991 • 27 citations

Effects of Bradykinin and Endothelin-1 on the Calcium Homeostasis of Mammalian Cells

1995 • 26 citations