Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

1991 • 875 citations

Chimeric α ₂ -,β ₂ -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity

1988 • 766 citations

Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function.

1988 • 533 citations

Molecular characterization of a functional cDNA for rat substance P receptor

1989 • 463 citations

Ligand binding to the β-adrenergic receptor involves its rhodopsin-like core

1987 • 318 citations

Cloning and expression of a rat neuromedin K receptor cDNA.

1990 • 308 citations

OPC-21268, an Orally Effective, Nonpeptide Vasopressin V1 Receptor Antagonist

1991 • 274 citations

Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK ₁ ) Receptor Antagonist

1991 • 221 citations

Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.

1985 • 193 citations

Localization of agonist and antagonist binding domains of the human neurokinin-1 receptor.

1992 • 190 citations

The tachykinins: a family of peptides with a brood of ‘receptors’

1986 • 164 citations

Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors

1990 • 160 citations

Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors.

1988 • 160 citations

Site-directed mutagenesis of the m3 muscarinic receptor: identification of a series of threonine and tyrosine residues involved in agonist but not antagonist binding.

1991 • 152 citations

A synthetic peptide as an antagonist of substance P

1981 • 144 citations

Immunomodulation by Tachykinin Neuropeptidesa

1990 • 126 citations

Neuropeptides And Their Receptors

1990 • 54 citations

Effect of CP-96,345, a nonpeptide substance P receptor antagonist, on salivation in rats.

1991 • 48 citations

Stable expression of high affinity NK₁ (substance P) and NK₂(neurokinin A) receptors but low affinity NK₃ (neurokinin B) receptors in transfected CHO cells

1992 • 34 citations

Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea

1984 • 28 citations

C-terminal KDEL-modified cystatin C is retained in transfected CHO cells

1990 • 11 citations

Neuropeptides and their receptors : proceedings of the Alfred Benzon Symposium 29 held at the premises of the Royal Danish Academy of Sciences and Letters, Copenhagen, 20-24 August 1989

1990 • 3 citations