Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Thickness, Cross-Sectional Areas and Depth of Invasion in the Prognosis of Cutaneous Melanoma

1970 • 2,415 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Human Retinoblastoma Susceptibility Gene: Cloning, Identification, and Sequence

1987 • 1,436 citations

Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule

1989 • 973 citations

A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma

1984 • 963 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

The Neural Cell Adhesion Molecule (NCAM) as a Regulator of Cell-Cell Interactions

1988 • 790 citations

Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule.

1983 • 635 citations

Cell Adhesion Molecules in the Regulation of Animal Form and Tissue Pattern

1986 • 630 citations

The Sequential Analysis of Cancer Development

1980 • 613 citations

Tumor interactions with the vasculature: angiogenesis and tumor metastasis

1990 • 598 citations

Preoperative Carcinoembryonic Antigen Level as a Prognostic Indicator in Colorectal Cancer

1978 • 471 citations

MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily.

1989 • 449 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

Cell adhesion molecules in vertebrate neural development.

1988 • 386 citations

De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis.

1989 • 367 citations

Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.

1988 • 330 citations

The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment--twenty-seventh G.H.A. Clowes memorial award lecture.

1988 • 326 citations

Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions.

1990 • 274 citations

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: Homophilic and heterophilic adhesion

1989 • 236 citations

Discrimination between benign and malignant cells of melanocytic lineage by two novel antigens, a glycoprotein with a molecular weight of 113,000 and a protein with a molecular weight of 76,000.

1987 • 210 citations

Carcinoembryonic Antigen as a Selective Enhancer of Colorectal Cancer Metastasis

1990 • 196 citations

Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms tumor.

1988 • 187 citations

Tumor progression in human malignant melanoma: Five stages defined by their antigenic phenotypes

1987 • 173 citations

The Carcinoembryonic Antigen Gene Family: Structure, Expression and Evolution

1988 • 156 citations

Loss of HLA-A,B,C allele products and lymphocyte function-associated antigen 3 in colorectal neoplasia.

1989 • 119 citations

LEUCOCYTE ADHESION TO CELLS IN IMMUNE AND INFLAMMATORY RESPONSES

1989 • 111 citations

On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules.

1990 • 107 citations

Differential effects of the cytoplasmic domains of cell adhesion molecules on cell aggregation and sorting-out.

1990 • 99 citations

HLA-DR histocompatibility leukocyte antigens permit cultured human melanoma cells from early but not advanced disease to stimulate autologous lymphocytes.

1984 • 96 citations

Histocompatibility antigens in primary and metastatic squamous cell carcinoma of the larynx

1989 • 92 citations

The role of polymorphonuclear leukocytes (PMN) on the growth and metastatic potential of 13762nf mammary adenocarcinoma cells

1988 • 72 citations

Growth potential of human colorectal carcinomas in nude mice: association with the preoperative serum concentration of carcinoembryonic antigen in patients.

1988 • 72 citations

Enhanced Tumorigenicity, Melanogenesis, and Metastases of a Human Malignant Melanoma After Subdermal Implantation in Nude Mice

1989 • 70 citations

Icam ‐ melanoma cells are relatively resistant to cd3‐mediated t‐cell lysis

1990 • 63 citations

Influence of migratory blood cells on the attachment of tumor cells to vascular endothelium

1984 • 63 citations

Human Lung Tumors, Patients’ Peripheral Blood Lymphocytes and Tumor Infiltrating Lymphocytes Propagated in Scid Mice

1989 • 55 citations

The Melanoma Progression-Associated Antigen P3.58 is Identical to the Intercellular Adhesion Molecule, ICAM-1

1988 • 53 citations

In situ analysis of antigens on malignant and benign cells of the melanocyte lineage. Differential expression of two surface molecules, gp75 and p89.

1985 • 53 citations

Molecular neurobiology

1990 • 33 citations

Effect of heterogeneity of carcinoembryonic antigen on liver cell membrane binding and its kinetics of removal from circulation.

1985 • 23 citations

Presence of neural cell adhesion molecule on human embryonic and brain tumours

1990 • 13 citations

Receptor-mediated endocytosis by human Kupffer cells

1988 • 11 citations

Prognostic Factors for Cutaneous Melanoma

1984 • 5 citations

Melanoma Antigens and Their Association with Malignant Transformation and Tumor Progression

1990 • 4 citations