Effects of reduced glutathione on the 12-lipoxygenase pathways in rat platelets

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

1974 • 1,410 citations

Arachidonate lipoxygenase in blood platelets

1975 • 613 citations

Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway.

1979 • 206 citations

Altered lipoxygenase metabolism and decreased glutathione peroxidase activity in platelets from selenium-deficient rats

1980 • 143 citations

Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.

1980 • 118 citations

Selective inhibition of platelet n — 8 lipoxygenase by 5,8,11-eicosatriynoic acid

1977 • 118 citations

Isolation of a new lipoxygenase metabolite of arachidonic acid, 8,11,12-trihydroxy-5,9,14-eicosatrienoic acid from human platelets

1979 • 100 citations

The identification of trihydroxyeicosatrienoic acids as products from the incubation of arachidonic acid with washed blood platelets

1978 • 99 citations

A new prostaglandin transformed from arachidonic acid in carrageenin-induced granuloma

1976 • 79 citations

Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds

1981 • 69 citations

Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma

1977 • 60 citations

Role of prostaglandin E in carrageenin-induced inflammation in rats

1976 • 44 citations

Isolation of glucose-sensitive platelet lipoxygenase products from arachidonic acid.

1980 • 20 citations