Aging under glass

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Death in Embryonic Systems

1966 • 943 citations

Production of Malignancy in Vitro. IV. The Mouse Fibroblast Cultures and Changes Seen in the Living Cells

1943 • 843 citations

Cultivation of the Lansing Strain of Poliomyelitis Virus in Cultures of Various Human Embryonic Tissues

1949 • 739 citations

The Maintenance of Human Normal Cells and Tumor Cells in Continuous Culture: I. Preliminary Report: Cultivation of Mesoblastic Tumors and Normal Tissue and Notes on Methods of Cultivation

1936 • 598 citations

Methods of tissue culture

1961 • 340 citations

The uniqueness of the individual

1957 • 315 citations

Decline in colony‐forming ability of marrow cells subjected to serial transplantation into irradiated mice

1964 • 276 citations

The division cycle and RNA-synthesis in diploid human cells at different passage levels in vitro

1966 • 271 citations

Growth: including reproduction and morphological development.

1962 • 258 citations

Ageing : the biology of senescence

1964 • 253 citations

The uniqueness of the individual

1957 • 248 citations

Ageing: The Biology of Senescence

1964 • 231 citations

HOW MANY CELL-GENERATIONS ?

1965 • 206 citations

Methods of Tissue Culture

1962 • 194 citations

Viability of human diploid cells as a function ofin vitro age

1969 • 175 citations

LIFESPAN OF CULTURED CELLS IN PROGERIA

1969 • 149 citations

Aging in Cell and Tissue Culture

1970 • 146 citations

Action of cortisone on human fibroblasts in vitro

1966 • 135 citations

Lymphocyte Content and Proliferative Capacity of Serially Transplanted Mouse Bone Marrow

1964 • 110 citations

Biological mechanisms of aging

1967 • 109 citations

Errors in Protein Synthesis and Clonal Senescence in Fungi

1969 • 104 citations

The use of frequency distributions of cell diameters to characterize cell populations in tissue culture

1967 • 103 citations

Biological Mechanisms of Aging

1963 • 95 citations

The Biology of Death

1923 • 83 citations

ANALOGY IN GROWTH BETWEEN LATE PASSAGE HUMAN EMBRYONIC AND EARLY PASSAGE HUMAN ADULT FIBROBLASTS

1969 • 76 citations

Respiration and glycolysis in the human diploid cell strain wi‐38

1966 • 75 citations

Transplantable and transmissible tumors of animals

1959 • 69 citations

THE PERMANENT LIFE OF CONNECTIVE TISSUE OUTSIDE OF THE ORGANISM

1913 • 65 citations

MEASUREMENT OF THE GROWTH OF TISSUES IN VITRO

1921 • 63 citations

Senescence and the Fidelity of Protein Synthesis in Drosophila

1967 • 63 citations

Induction of collagenolytic and proteolytic activities by anti-inflammatory drugs in the skin and fibroblast

1968 • 56 citations

The source of cellular lipid in the human diploid cell strain WI-38

1969 • 55 citations

Transplantable and Transmissible Tumors of Animals

1959 • 51 citations

The lipids of normal diploid (WI‐38) and sv40‐transformed human cells

1969 • 49 citations

The latent period of explanted organs of newborn, adult and senile rats

1964 • 48 citations

Inheritance of the “life-spanning” phenomenon in Amoeba proteus

1968 • 48 citations

Some Alternative States of Amoeba, with Special Reference to Life-Span

1959 • 35 citations

CHOLESTEROL REQUIREMENT OF PRIMARY DIPLOID HUMAN FIBROBLASTS

1969 • 33 citations

Induction of Collagenolytic and Proteolytic Activities in Rat and Human Fibroblasts by Anti-Inflammatory Drugs

1968 • 31 citations

Perspectives in experimental gerontology

1967 • 31 citations

Absence of a life-shortening effect of amino-acid analogues on adult Drosophila

1969 • 24 citations

The Mortality of Plaice

1925 • 21 citations

The effect of donor age on the emigration of cells from chick embryo explants in vitro*1

1964 • 20 citations

Prolongation of Postmitotic Life-span of Primary Human Amnion Cells in Vitro by Hydrocortisone

1967 • 19 citations

Mitochondrial enzyme activity in “senescent” and virus-transformed human fibroblasts

1968 • 18 citations

Metabolic Alterations with Senescence of Human Cells

1962 • 15 citations

Behaviour of Explanted Kidney Cells from Young, Adult and Old Rats

1965 • 13 citations

Mitotic index in vitro of embryonic heart fibroblasts of different donor ages

1962 • 11 citations

Ageing of cells in cell and tissue culture

1968 • 11 citations