Recombinant Granulocyte Colony-Stimulating Factor (rG-CSF)

The Human Hematopoietic Colony-Stimulating Factors

1987 • 1,728 citations

Reduction by Granulocyte Colony-Stimulating Factor of Fever and Neutropenia Induced by Chemotherapy in Patients with Small-Cell Lung Cancer

1991 • 1,401 citations

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium

1988 • 961 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

EFFECT OF GRANULOCYTE COLONY STIMULATING FACTOR ON NEUTROPENIA INDUCED BY CYTOTOXIC CHEMOTHERAPY

1988 • 740 citations

Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate

1989 • 652 citations

Hematopoietic growth factors.

1987 • 621 citations

Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer

1987 • 605 citations

Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients

1988 • 600 citations

Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor.

1983 • 568 citations

Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor.

1985 • 522 citations

Effects of Recombinant Human Granulocyte Colony-Stimulating Factor on Neutropenia in Patients with Congenital Agranulocytosis

1989 • 495 citations

The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

1986 • 492 citations

GRANULOCYTE COLONY-STIMULATING FACTOR AND NEUTROPHIL RECOVERY AFTER HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS BONE MARROW TRANSPLANTATION

1989 • 440 citations

Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

1987 • 428 citations

Effect of Granulocyte Colony-Stimulating Factor after Intensive Induction Therapy in Relapsed or Refractory Acute Leukemia

1990 • 403 citations

Treatment of Cyclic Neutropenia with Granulocyte Colony-Stimulating Factor

1989 • 363 citations

Granulocyte-macrophage colony-stimulating factor enhances phagocytosis of bacteria by human neutrophils

1986 • 331 citations

Differential effects of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in children with severe congenital neutropenia

1990 • 289 citations

The use of granulocyte colony-stimulating factor to increase the intensity of treatment with doxorubicin in patients with advanced breast and ovarian cancer

1989 • 267 citations

Hemopoietic Growth Factors: A Review

1992 • 239 citations

Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor

1990 • 238 citations

Phase I study of granulocyte colony-stimulating factor in patients with transitional cell carcinoma of the urothelium.

1988 • 233 citations

Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells

1985 • 233 citations

In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor.

1987 • 231 citations

Evidence for a novel in vivo control mechanism of granulopoiesis: mature cell-related control of a regulatory growth factor

1989 • 231 citations

Proliferative effects of purified granulocyte colony‐stimulating factor (G‐CSF) on normal mouse hemopoietic cells

1983 • 221 citations

Treatment of Myelodysplastic Syndromes with Recombinant Human Granulocyte Colony-Stimulating Factor

1989 • 208 citations

Independent regulation of M-CSF and G-CSF gene expression in human monocytes

1988 • 200 citations

Hematologic effects of recombinant human granulocyte colony-stimulating factor in patients with malignancy

1989 • 200 citations

Therapy for Neutropenia in Hairy Cell Leukemia with Recombinant Human Granulocyte Colony-Stimulating Factor

1988 • 196 citations

Activation of granulocyte cytotoxic function by purified mouse colony-stimulating factors.

1983 • 193 citations

Recombinant human granulocyte colony-stimulating factor hastens granulocyte recovery after high-dose chemotherapy and autologous bone marrow transplantation in Hodgkin's disease.

1989 • 188 citations

In vitro and in vivo analysis of the effects of recombinant human granulocyte colony-stimulating factor in patients

1988 • 187 citations

Treatment of chemotherapy-induced neutropenia by subcutaneously administered granulocyte colony-stimulating factor with optimization of dose and duration of therapy.

1989 • 181 citations

Biological activities of a human pluripotent hemopoietic colony stimulating factor on normal and leukemic cells.

1985 • 175 citations

Effects of Human Granulocyte Colony-Stimulating Factor in a Patient with Idiopathic Neutropenia

1989 • 164 citations

Growth regulation of human acute myeloid leukemia: effects of five recombinant hematopoietic factors in a serum-free culture system

1988 • 162 citations

Protective effect of human granulocyte colony-stimulating factor on microbial infection in neutropenic mice

1987 • 160 citations

Colony-Stimulating Factors and Host Defense

1989 • 155 citations

Granulocyte colony-stimulating factor stimulates recovery of granulocytes in patients receiving dose-intensive chemotherapy without bone marrow transplantation.

1989 • 150 citations

In vivo activation of human neutrophil functions by administration of recombinant human granulocyte colony-stimulating factor in patients with malignant lymphoma

1989 • 149 citations

Why do hemopoietic growth factor receptors interact with each other?

1987 • 148 citations

Chronic Neutropenia

1979 • 146 citations

Induction of neutrophilic granulocytosis in mice by administration of purified human native granulocyte colony-stimulating factor (G-CSF)

1987 • 141 citations

Treatment of aplastic anemia in children with recombinant human granulocyte colony-stimulating factor

1991 • 138 citations

Localization of the G-CSF gene on chromosome 17 proximal to the breakpoint in the t(15;17) in acute promyelocytic leukemia

1987 • 135 citations

Combined therapy with recombinant granulocyte colony-stimulating factor and erythropoietin decreases hematologic toxicity from zidovudine

1991 • 133 citations

Purified colony stimulating factors (G‐CSF and GM‐CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity

1987 • 125 citations

A Simple In Vitro Method for Studies on Chemotaxis

1974 • 118 citations

Structural Characterization of Natural and Recombinant Human Granulocyte Colony-Stimulating Factors1

1990 • 116 citations

Therapeutic Use of Recombinant Human G-CSF (rhG-CSF) in a Canine Model of Sublethal and Lethal Whole-body Irradiation

1990 • 115 citations

Treatment of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor: A preliminary report

1989 • 109 citations

Autoinduction of differentiation in wehi‐3B leukemia cells

1982 • 105 citations

Kinetics and mechanisms of recombinant human granulocyte-colony stimulating factor-induced neutrophilia.

1988 • 103 citations

The contribution of blast cell properties to outcome variation in acute myeloblastic leukemia (AML)

1982 • 102 citations

Disulfide and secondary structures of recombinant human granulocyte colony stimulating factor

1989 • 99 citations

In vivo radioprotective effects of recombinant human granulocyte colony- stimulating factor in lethally irradiated mice

1990 • 94 citations

Prophylactic or Simultaneous Administration of Recombinant Human Granulocyte Colony Stimulating Factor in the Treatment of Group B Streptococcal Sepsis in Neonatal Rats

1990 • 93 citations

Actions and interactions of G-CSF, LIF, and IL-6 on normal and leukemic murine cells.

1989 • 93 citations

Action of interleukin-3, G-CSF, and GM-CSF on highly enriched human hematopoietic progenitor cells: synergistic interaction of GM-CSF plus G-CSF

1989 • 87 citations

Therapeutic efficacy of granulocyte colony-stimulating factor alone and in combination with antibiotics against Pseudomonas aeruginosa infections in mice

1990 • 82 citations

Effects of recombinant human granulocyte colony-stimulating factor on the hematologic recovery and survival of irradiated mice

1990 • 79 citations

Seven-day administration of recombinant human granulocyte colony- stimulating factor to newborn rats: modulation of neonatal neutrophilia, myelopoiesis, and group B Streptococcus sepsis

1990 • 79 citations

In vivo activation of neutrophil function in hamsters by recombinant human granulocyte colony-stimulating factor

1988 • 78 citations

Granulocyte colony-stimulating factor augments in vitro megakaryocyte colony formation by interleukin-3.

1988 • 73 citations

Hemopoietic effects of short-term in vivo treatment of mice with various doses of rhG-CSF.

1990 • 70 citations

Effect of granulocyte colony-stimulating factor on neutropenia due to chemotherapy for non-Hodgkin's lymphoma

1990 • 66 citations

Recombinant human granulocyte colony-stimulating factor induces granulocytosis in vivo.

1986 • 65 citations

The effect of recombinant human colony-stimulating factors on hematopoietic reconstitution following autologous bone marrow transplantation.

1989 • 62 citations

Clinical experience with recombinant human granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor.

1989 • 58 citations

The hematologic effects of chronic administration of the monokines tumor necrosis factor, interleukin-1, and granulocyte-colony stimulating factor on bone marrow and circulation.

1989 • 56 citations

Growth response of human myeloid leukemia cells to colony-stimulating factors.

1988 • 55 citations

Clinical effects of recombinant human granulocyte colony-stimulating factor in leukemia patients: a phase I/II study.

1989 • 54 citations

Hematopoietic progenitors in cyclic neutropenia: effect of granulocyte colony-stimulating factor in vivo

1990 • 53 citations

Dose escalation study of recombinant human granulocyte-colony-stimulating factor (KRN8601) in patients with advanced malignancy.

1989 • 52 citations

Recombinant human granulocyte colony-stimulating factor increases circulating burst forming unit-erythron and red blood cell production in patients with severe human immunodeficiency virus infection

1990 • 51 citations

Efficacy of recombinant human granulocyte colony-stimulating factor on neutropenia in patients with AIDS

1990 • 50 citations

Effects of recombinant human granulocyte colony-stimulating factor (G-CSF) on blast progenitors from acute myeloblastic leukaemia patients

1987 • 49 citations

Effects of recombinant human granulocyte-colony stimulating factor on hematopoietic reconstitution after autologous bone marrow transplantation in primates.

1987 • 48 citations

Review of G-CSF and GM-CSF. Effects on neonatal neutrophil kinetics.

1989 • 47 citations

Peripheral Blood Morphologic Changes after High-Dose Antineoplastic Chemotherapy and Recombinant Human Granulocyte Colony-Stimulating Factor Administration

1989 • 47 citations

Clinical and biologic effects of granulocyte colony stimulating factor in the treatment of myelokathexis

1991 • 47 citations

Preclinical studies on synergistic effects of IL-1, IL-3, G-CSF and GM-CSF in cynomolgus monkeys

1990 • 46 citations

Introduction and overview of hematopoietic growth factors.

1989 • 43 citations

The chronic idiopathic neutropenia syndrome: correlation of clinical features with in vitro parameters of granulocytopoiesis

1980 • 41 citations

Synergistic effects between GM-CSF and G-CSF or M-CSF on highly enriched human marrow progenitor cells.

1990 • 40 citations

Human granulocyte colony-stimulating factor produced by Escherichia coli shortens the period of granulocytopenia induced by irradiation in mice.

1987 • 40 citations

Human granulocyte colony-stimulating factor: its biological actions and clinical implication.

1987 • 37 citations

Survival enhancement and hemopoietic regeneration following radiation exposure: therapeutic approach using glucan and granulocyte colony-stimulating factor.

1990 • 34 citations

In vivo effects of recombinant colony stimulating factors on hematopoiesis in cynomolgus monkeys.

1989 • 30 citations

Effect of recombinant human granulocyte colony-stimulating factor on granulocytopenia in mice induced by irradiation

1990 • 28 citations

Recombinant human IL-3 and G-CSF act synergistically in stimulating the growth of acute myeloid leukemia cells.

1989 • 27 citations

Effects of Interleukin‐6 and Granulocyte Colony‐stimulating Factor on the Proliferation of Leukemic Blast Progenitors from Acute Myeloblastic Leukemia Patients

1990 • 25 citations

Neutrophil kinetics in chronic neutropenia

1979 • 22 citations

Neutrophil marrow in chronic benign idiopathic neutropenia

1980 • 16 citations

Effects of recombinant human granulocyte colony stimulating factor (rG-CSF) on murine myeloid leukemia: stimulation of proliferation of leukemic cells in vitro and inhibition of development of leukemia in vivo.

1989 • 15 citations

Neutrophil kinetics of recombinant human granulocyte colony-stimulating factor-induced neutropenia in rats

1990 • 15 citations

Recombinant human granulocyte colony-stimulating factor accelerates hematopoietic recovery after DLA-identical littermate marrow transplants in dogs

1990 • 15 citations

The use of myeloid hematopoietic growth factors in patients with HIV infection

1990 • 14 citations

Mechanism of synergy between granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in colony formation from human marrow cells in vitro.

1989 • 14 citations

Colony Stimulating Activities of GM-CSF, G-CSF and IL-3 on Blast Progenitors from Acute Myeloblastic Leukemia

1990 • 9 citations

[A double-blind, cross-over clinical trial of recombinant human G-CSF on neutropenia induced by chemotherapy for non-Hodgkin's lymphoma].

1990 • 8 citations

Effects of recombinant human G-CSF and GM-CSF on primary human leukemic cells.

1989 • 8 citations

Study of the Prophylactic and Therapeutic Effect of Human Granulocyte-Colony Stimulating Factor (G-CSF) on Experimental Pyelonephritis Induced by Pseudomonas Aeruginase in Neutropenic Mice

1989 • 6 citations

[The effect of recombinant human granulocyte colony-stimulating factor (rG-CSF) on childhood neutropenias].

1991 • 5 citations

No home yet for radiation source

1985 • 5 citations

[Effects of recombinant human G -and GM-CSF on the proliferation of leukemic blast progenitors from acute myeloblastic leukemia patients].

1988 • 4 citations

In Vitro Effects of G-CSF, GM-CSF, and IL-3 on Leukemic Cells of Children with Acute Nonlymphoblastic Leukemia

1990 • 4 citations

Hematopoietic growth factors in marrow transplantation and radiation injury.

1990 • 3 citations