Initiation of Bone Development by Osteogenin and Promotion by Growth Factors

Bone: Formation by Autoinduction

1965 • 5,498 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Biochemical Sequences in the Transformation of Normal Fibroblasts in Adolescent Rats

1972 • 815 citations

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

1985 • 738 citations

Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation.

1981 • 585 citations

Cartilage-inducing factor-A. Apparent identity to transforming growth factor-beta.

1986 • 533 citations

Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions

1985 • 366 citations

Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography.

1987 • 334 citations

Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix.

1983 • 318 citations

Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants

1988 • 310 citations

Isolation and Characterization of Insulin-Like Growth Factor I (Somatomedin-C) from Cultures of Fetal Rat Calvariae*

1988 • 188 citations

Transforming and nontransforming growth factors are present in medium conditioned by fetal rat calvariae.

1985 • 161 citations

Accumulation, localization, and compartmentation of transforming growth factor beta during endochondral bone development.

1988 • 154 citations

Synthesis and localization of fibronectin during collagenous matrix-mesenchymal cell interaction and differentiation of cartilage and bone in vivo.

1980 • 150 citations

Effect of platelet-derived growth factor on DNA and protein synthesis in cultured rat calvaria

1981 • 127 citations

Platelet-derived growth factor enhances demineralized bone matrix-induced cartilage and bone formation

1988 • 89 citations

Collagenous bone matrix is a local mitogen

1979 • 76 citations

Dose-dependence of and Threshold for Optimal Bone Induction by Collagenous Bone Matrix and Osteogenin-enriched Fraction

1988 • 69 citations

Role of fibronectin in collagenous matrix-induced mesenchymal cell proliferation and differentiation in vivo

1981 • 66 citations

Coagulation of Blood Plasma of Guinea Pig by the Bone Matrix

1973 • 18 citations

COLLAGENOUS BONE MATRIX AND GENE EXPRESSION IN FIBROBLASTS

1975 • 13 citations