Back to search

Nitric Oxide Mediates Hepatic Cytochrome P450 Dysfunction Induced by Endotoxin

Data up to Jan 2025

Published1996
Citations59
References29

Total Citations Per Year

Abstract

References (29)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1953 • 4,357 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1991 • 873 citations

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1993 • 734 citations

Nitrogen Oxide Levels in Patients After Trauma and During Sepsis

1991 • 609 citations

Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs

1988 • 539 citations

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

1989 • 528 citations

Inhibition of Cytochromes P450 by Nitric Oxide and a Nitric Oxide-Releasing Agent

1993 • 358 citations

Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants.

1993 • 287 citations

Multiple Cytokines Are Required to Induce Hepatocyte Nitric Oxide Production and Inhibit Total Protein Synthesis

1990 • 273 citations

Oxidation and reduction of hemoproteins by trioxodinitrate(II). The role of nitrosyl hydride and nitrite

1988 • 212 citations

Altered Theophylline Clearance During an Influenza B Outbreak

1982 • 197 citations

Cytochrome P-450 heme and the regulation of hepatic heme oxygenase activity

1976 • 174 citations

Studies of the oxygen binding site of cytochrome P-450. Nitric oxide as a spin-label probe.

1978 • 134 citations

High‐level expression of functional human cytochrome P450 1A2 in Escherichia coli

1992 • 111 citations

Hepatic microsomal drug metabolism after administration of endotoxin in rats

1976 • 108 citations

Turnover of membrane proteins: Kinetics of induction and degradation of seven forms of rat liver microsomal cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydrolase

1984 • 100 citations

Regulation of cytochrome P450IIC12 expression by interleukin-1 alpha, interleukin-6, and dexamethasone.

1991 • 86 citations

Properties of a Submicrosomal Particle Containing P-450 and Flavoprotein

1968 • 84 citations

Dexamethasone Modulation of In Vivo Effects of Endotoxin, Tumor Necrosis Factor, and Interleukin-1 on Liver Cytochrome P-450, Plasma Fibrinogen, and Serum Iron

1989 • 72 citations

Endotoxin and TNFα directly stimulate nitric oxide formation in cultured rat hepatocytes from chronically endotoxemic rats

1992 • 58 citations

Interleukin-6 production by endotoxin-stimulated kupffer cells is regulated by prostaglandin E2

1990 • 47 citations

Human fetal and adult liver metabolism of ethylmorphine

1989 • 44 citations

Determination of endothelium-derived nitrite/nitrate by gas chromatography/tandem mass spectrometry using (15N)NaNO2 as internal standard

1992 • 34 citations

Cited By (0)

No citing papers found in database

Nitric Oxide Mediates Hepatic Cytochrome P450 Dysfunction Induced by Endotoxin (1996) – Anesthesiology | Metascience Observatory Explorer