Cellular Thiols Redox Status: a Switch for NF-κB Activation During Myocardial Post-ischaemic Reperfusion

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent

1968 • 7,671 citations

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity

1995 • 1,287 citations

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 • 1,129 citations

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.

1996 • 1,045 citations

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

1990 • 960 citations

A spectrophotometric method for the determination of creative phosphokinase and myokinase

1955 • 719 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Inhibition of TNF-induced apoptosis by NF-κB

1998 • 370 citations

Occurrence of oxidative stress during reperfusion of the human heart.

1990 • 297 citations

Intracellular oxidation/reduction status in the regulation of transcription factors NF-κB and AP-1

1999 • 266 citations

Reactive Oxygen Species as Mediators of Signal Transduction in Cardiovascular Disease

1998 • 261 citations

Ischemic Preconditioning Reduces Apoptosis By Upregulating Anti-Death Gene Bcl-2

1999 • 216 citations

Early activation of transcription factor NF-κB during ischemia in perfused rat heart

1999 • 213 citations

The role of glutathione status in the protection against ischaemic and reperfusion damage: Effects of N-acetyl cysteine

1988 • 178 citations

Induction of nuclear factor κB and activation protein 1 in postischemic myocardium

1997 • 160 citations

Acidosis Inhibits Endothelial Cell Apoptosis and Function and Induces Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor Expression

2000 • 148 citations

Molecular Mechanisms of Neutrophil-Endothelial Cell Adhesion Induced by Redox Imbalance

1999 • 134 citations

Mechanisms by which IκB proteins control NF-κB activity

1999 • 134 citations

Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts

1999 • 116 citations

Glutathione redox pathway and reperfusion injury. Effect of N-acetylcysteine on infarct size and ventricular function.

1988 • 113 citations

Transcription factors : a practical approach

1993 • 94 citations

Inhibition of nuclear factor κB attenuates proinflammatory cytokine and inducible nitric-oxide synthase expression in postischemic myocardium

1998 • 89 citations

Thiol dependent oxidation of enzymes: The last chance against oxidative stress

1994 • 86 citations

Metabolic Adaptation During a Sequence of No-Flow and Low-Flow Ischemia

1996 • 77 citations

Glutathione Downregulates the Phosphorylation of IκB: Autoloop Regulation of the NF-κB-Mediated Expression of NF-κB Subunits by TNF-α in Mouse Vascular Endothelial Cells

1998 • 66 citations

Overexpression of A1, an NF-κB–Inducible Anti-Apoptotic Bcl Gene, Inhibits Endothelial Cell Activation

1999 • 54 citations

Differential activation of some transcription factors during rat liver ischemia, reperfusion, and heat shock

1999 • 47 citations