Immunoglobulin production in cultures of pokeweed mitogen stimulated human peripheral blood mononuclear cells requires interaction of interleukin 2 with the B cells

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

1982 • 877 citations

Expression of interleukin 2 receptors on activated human B cells.

1984 • 488 citations

Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells

1984 • 375 citations

Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.

1984 • 361 citations

Expression of Tac antigen on activated normal human B cells.

1984 • 355 citations

Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation.

1983 • 250 citations

Effect of recombinant IL 2 and gamma-IFN on proliferation and differentiation of human B cells.

1985 • 216 citations

B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and their synergism in B cell proliferation.

1983 • 182 citations

B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor.

1981 • 159 citations

Interleukin 2 induces antigen-reactive T cell lines to secrete BCGF-I.

1983 • 136 citations

In vitro immune response of human peripheral lymphocytes. I. The mechanism(s) involved in T cell helper functions in the pokeweed mitogen-induced differentiation and proliferation of B cells.

1977 • 133 citations

Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis.

1984 • 106 citations

Development of a human T-T cell hybridoma secreting B cell growth factor.

1983 • 104 citations

Soluble factors involved in B cell differentiation: identification of two distinct T cell-replacing factors (TRF).

1983 • 101 citations

Regulation of immunoglobulin production in pokeweed mitogen-stimulated cultures of lymphocytes from young and old adults.

1982 • 84 citations

In Vitro Immune Response of Human Peripheral Lymphocytes

1977 • 65 citations

The presence of Ia antigen on human peripheral blood T cells and T-cell subsets: Analysis with monoclonal antibodies and the fluorescence-activated cell sorter

1981 • 50 citations

Regulation of human B-cell activation, proliferation, and differentiation by soluble factors

1984 • 49 citations

Induction of immunoglobulin synthesis by interleukin 2 is T4⁺/T8⁻ cell dependent. A role for interleukin 2 in the pokeweed mitogen‐driven system

1985 • 48 citations