II. Selective accumulation of MPP+ in the substantia nigra: A key to neurotoxicity?

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

1979 • 1,356 citations

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1984 • 1,092 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1984 • 772 citations

Pargyline Prevents MPTP-Induced Parkinsonism in Primates

1984 • 575 citations

1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra

1984 • 423 citations

Melanin Affinity of 1‐Methyl‐4‐phenyl‐1,2,5,6‐tetrahydropyridine, an Inducer of Chronic Parkinsonism in Humans

1983 • 67 citations

PIPERIDINE DERIVATIVES. PART III. 4-ARYLPIPERIDINES¹

1947 • 63 citations

The mechanism of the reduction of pyridinium ions with sodium borohydride

1962 • 36 citations