Expression and antigenicity of Plasmodium falciparum major merozoite surface protein (MSP119) variants secreted from Saccharomyces cerevisiae

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

1990 • 562 citations

Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1)

1993 • 389 citations

A vaccine candidate from the sexual stage of human malaria that contains EGF-like domains

1988 • 375 citations

Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria.

1987 • 311 citations

Proteolytic processing of thePlasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains

1991 • 237 citations

Recombinant Pfs25 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in experimental animals.

1991 • 217 citations

The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor.

1984 • 191 citations

A recombinant 15-kilodalton carboxyl-terminal fragment of Plasmodium yoelii yoelii 17XL merozoite surface protein 1 induces a protective immune response in mice

1993 • 189 citations

A malaria merozoite surface protein (MSP1)-structure, processing and function

1992 • 182 citations

A carboxyl-terminal fragment of Plasmodium falciparum gp195 expressed by a recombinant baculovirus induces antibodies that completely inhibit parasite growth.

1992 • 150 citations

Monoclonal antibodies that inhibit Plasmodium falciparum invasion in vitro recognise the first growth factor-like domain of merozoite surface protein-1

1993 • 145 citations

Characterization with monoclonal antibodies of a surface antigen of Plasmodium falciparum merozoites.

1985 • 110 citations

Expression, purification and characterization of recombinant marine granulocyte-macrophage colony-stimulating factor and bovine interleukin-2 from yeast

1987 • 86 citations

Mapping of the region predominantly recognized by antibodies to the Plasmodium falciparum merozoite surface antigen MSA 1

1992 • 79 citations

Sequence conservation in the C-terminal part of the precursor to the major merozoite surface proteins (MSP1) ofPlasmodium falciparum from field isolates

1993 • 51 citations

Roles of conserved and allelic regions of the major merozoite surface protein (gp195) in immunity against Plasmodium falciparum

1992 • 27 citations

Immunological cross-reactivity of the C-terminal 42-kilodalton fragment of Plasmodium falciparum merozoite surface protein 1 expressed in baculovirus

1993 • 22 citations