Mice deficient in ubiquitous mitochondrial creatine kinase are viable and fertile

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis

1992 • 1,958 citations

HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

1987 • 1,231 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Transport of Energy in Muscle: The Phosphorylcreatine Shuttle

1981 • 748 citations

Cilia and flagella of eukaryotes.

1981 • 611 citations

Do defecs in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?

1993 • 583 citations

Mitochondrial creatine kinase: a key enzyme of aerobic energy metabolism

1992 • 439 citations

Creatine Deficiency in the Brain: A New, Treatable Inborn Error of Metabolism

1994 • 407 citations

Creatine kinase in non-muscle tissues and cells

1994 • 372 citations

Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity

1993 • 334 citations

Molecular biology of human male infertility: Links with aging, mitochondrial genetics, and oxidative stress?

1994 • 298 citations

Effect of incubation volume and embryo density on the development and viability of mouse embryos in vitro

1992 • 267 citations

Age‐Dependent Impairment of Mitochondrial Function in Primate Brain

1993 • 265 citations

Teratocarcinomas and Embryonic Stem Cells: A Practical Approach

1988 • 263 citations

Metabolite channeling: A phosphorylcreatine shuttle to mediate high energy phosphate transport between sperm mitochondrion and tail

1985 • 247 citations

Relationships between the neuronal sodium/potassium pump and energy metabolism. Effects of K+, Na+, and adenosine triphosphate in isolated brain synaptosomes.

1990 • 161 citations

Sperm creatine phosphokinase M-isoform ratios and fertilizing potential of men: a blinded study of 84 couples treated with in vitro fertilization

1992 • 125 citations

Determination of creatine kinase kinetic parameters in rat brain by NMR magnetization transfer. Correlation with brain function

1993 • 106 citations

Creatine kinase-dependent energy transport in sea urchin spermatozoa. Flagellar wave attenuation and theoretical analysis of high energy phosphate diffusion

1987 • 102 citations

Creatine metabolism and the consequences of creatine depletion in muscle

1994 • 101 citations

Creatine kinase isoenzymes in spermatozoa

1986 • 93 citations

The cellular basis of cerebellar plasticity

1991 • 89 citations

Targeting of the creating kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors

1992 • 89 citations

Adenylate Kinase Activity in Ejaculated Bovine Sperm Flagella

1989 • 74 citations

Delineation of sites mediating estrogen regulation of the rat creatine kinase B gene.

1992 • 69 citations

Compartment of brain‐type cretine kinase and ubiquitous mitochondrial cretine kinase in neurons: Evidence for a cretine phosphate energy shuttle in adult rat brain

1994 • 66 citations

The effect of substrate cycling on the ATP yield of sperm glycolysis.

1983 • 66 citations

Only one of the two interconvertible forms of mitochondrial creatine kinase binds to heart mitoplasts

1987 • 64 citations

Tissue- and cell-specific distribution of creatine kinase B: A new and highly specific monoclonal antibody for use in immunohistochemistry

1995 • 60 citations

Functional Maturation of Creatine Kinase in Rat Brain

1993 • 52 citations

Creatine Kinase Isoenzymes in Chicken Cerebellum: Specific Localization of Brain‐type Creatine Kinase in Bergmann Glial Cells and Muscle‐type Creatine Kinase in Purkinje Neurons

1994 • 52 citations

31P-NMR analysis of sea urchin sperm activation

1983 • 48 citations

Compartmentation of multiple forms of creatine kinase in the distal nephron of the rat kidney.

1991 • 46 citations

Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells

1991 • 45 citations

Effects of the creatine analogue β-guanidinopropionic acid on skeletal muscles of mice deficient in muscle creatine kinase

1994 • 41 citations

Brain creatine phosphate and creatine kinase in mice fed an analogue of creatine

1989 • 38 citations

Expression of creatine kinase isoenzyme during oogenesis and embryogenesis in the mouse

1983 • 29 citations

Sea urchin sperm creatine kinase: The flagellar isozyme is a microtubule-associated protein

1988 • 26 citations

Developmental expression of sarcomeric and ubiquitous mitochondrial creatine kinase is tissue-specific

1994 • 25 citations

Membrane association of flagellar creatine kinase in the sperm phosphocreatine shuttle.

1991 • 25 citations

A Method for Quantitative Measurement of Mitochondrial Creatine Kinase in Human Skeletal Muscle

1992 • 21 citations

Creatine kinase isoenzymes

1988 • 20 citations

Mouse Ubiquitous Mitochondrial Creatine Kinase: Gene Organization and Consequences from Inactivation in Mouse Embryonic Stem Cells

1995 • 18 citations

Creatine kinase function in mitochondria isolated from gravid and non‐gravid guinea‐pig uteri

1994 • 17 citations

The influence of sperm density on the motility characteristics of washed human spermatozoa

1993 • 12 citations

EFFECTS OF ALTERED OSMOLALITY ON RESPIRATION AND MORPHOLOGY OF MITOCHONDRIA FROM THE DEVELOPING BRAIN

1979 • 9 citations

Deleted Work

1955 • 0 citations