Chicken Transcription Factor AP-2: Cloning, Expression and Its Role in Outgrowth of Facial Prominences and Limb Buds

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

The proximo‐distal sequence of origin of the parts of the chick wing and the role of the ectoderm

1948 • 1,101 citations

The triple origin of skull in higher vertebrates: a study in quail-chick chimeras

1993 • 981 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

Control of Cell Behavior During Vertebrate Development by Slug , a Zinc Finger Gene

1994 • 744 citations

Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb

1995 • 719 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny

1996 • 681 citations

Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo

1991 • 635 citations

Transcription factor AP-2 essential for cranial closure and craniofacial development

1996 • 611 citations

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

1996 • 595 citations

Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis.

1991 • 593 citations

Roles for FGF8 in the Induction, Initiation, and Maintenance of Chick Limb Development

1996 • 588 citations

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.

1988 • 578 citations

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2.

1991 • 519 citations

An analysis of the migratory behavior of avian cephalic neural crest cells

1975 • 493 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

Induction of the LIM homeobox gene Lmx1 by WNT6a establishes dorsoventral pattern in the vertebrate limb

1995 • 469 citations

Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb

1994 • 465 citations

Segmentation in the vertebrate nervous system

1984 • 440 citations

Origins of the avian neural crest: the role of neural plate-epidermal interactions

1995 • 423 citations

A radioautographic study of the migration and fate of cranial neural crest cells in the chick embryo

1966 • 421 citations

The control of avian cephalic neural crest cytodifferentiation

1978 • 417 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

Two rhombomeres are altered in Hoxa-1 mutant mice

1993 • 391 citations

A quantitative analysis of the effect of excision of the AER from the chick limb-bud

1974 • 376 citations

Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

1989 • 373 citations

Involvement of FGF8 in initiation, outgrowth and patterning of the vertebrate limb

1996 • 335 citations

Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization

1990 • 323 citations

Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb

1996 • 314 citations

Dorsal cell fate specified by chick Lmxl during vertebrate limb development

1995 • 287 citations

Participation of neural crest-derived cells in the genesis of the skull in birds

1978 • 262 citations

Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain

1993 • 260 citations

Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.

1989 • 260 citations

Hoxa-2 expression in normal and transposed rhombomeres: independent regulation in the neural tube and neural crest

1994 • 252 citations

Cloning and characterization of a second AP-2 transcription factor: AP-2β

1995 • 248 citations

A fate map of the epiblast of the early chick embryo

1994 • 232 citations

Ectopic application of recombinant BMP-2 and BMP-4 can change patterning of developing chick facial primordia

1997 • 222 citations

AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis

1996 • 185 citations

Position-dependent expression of two related homeobox genes in developing vertebrate limbs

1991 • 181 citations

Comparative analysis of AP-2α and AP-2β gene expression during murine embryogenesis

1997 • 164 citations

Expression patterns of the bone morphogenetic protein genes Bmp‐4 and Bmp‐2 in the developing chick face suggest a role in outgrowth of the primordia

1994 • 132 citations

Temporal and regional differences in the expression pattern of distinct retinoic acid receptor-β transcripts in the chick embryo

1991 • 131 citations

Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid

1991 • 120 citations

Epithelial–mesenchymal interactions in the development of chick facial primordia and the target of retinoid action

1987 • 117 citations

AP-2.2: A Novel AP-2-Related Transcription Factor Induced by Retinoic Acid during Differentiation of P19 Embryonal Carcinoma Cells

1996 • 115 citations

Retinoic acid-binding protein, rhombomeres and the neural crest

1991 • 114 citations

Epithelia are interchangeable between facial primordia of chick embryos and morphogenesis is controlled by the mesenchyme

1989 • 111 citations

The effect of cell killing by X-irradiation on pattern formation in the chick limb

1979 • 105 citations

The cellular retinoic-acid-binding protein is expressed in tissues associated with retinoic-acid-induced malformations

1990 • 101 citations

The expression pattern of the Distal-less homeo☐-containing gene Dlx-5 in the developing chick limb bud suggests its involvement in apical ectodermal ridge activity, pattern formation, and cartilage differentiation

1995 • 98 citations

Chromosomal Mapping of the Human and Mouse Homologues of Two New Members of the AP-2 Family of Transcription Factors

1996 • 89 citations

Experimental analysis of the control of expression of the homeobox-gene Msx-1 in the developing limb and face

1993 • 89 citations

Epithelial-mesenchymal interactions in the outgrowth of limb buds and facial primordia in chick embryos

1992 • 88 citations

Experimental analysis of Msx‐1 and Msx‐2 gene expression during chick mandibular morphogenesis

1995 • 85 citations

Pattern formation in the facial primordia.

1988 • 80 citations

Retinoic acid treatment alters the distribution of retinoic acid receptor-β transcripts in the embryonic chick face

1991 • 72 citations

Developmental regulation of transcription factor AP-2 duringXenopus laevisembryogenesis

1991 • 67 citations

Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds

1992 • 66 citations

Alternative mRNAs Encode Multiple Isoforms of Transcription Factor AP-2 during Murine Embryogenesis

1995 • 62 citations

The genomic structure of the human AP-2 transcription factor

1994 • 59 citations

Multiple sites of HOX‐7 expression during mouse embryogenesis: Comparison with retinoic acid receptor mRNA localization

1992 • 58 citations

Analysis of upper beak defects in chicken embryos following with retinoic acid

1984 • 57 citations

Cell Type-Specific Regulation of Expression of Transcription Factor AP-2 in Neuroectodermal Cells

1994 • 55 citations

Expression and regulation of Cek-8, a cell to cell signalling receptor in developing chick limb buds

1996 • 55 citations

Rhombomere rotation reveals that multiple mechanisms contribute to the segmental pattern of hindbrain neural crest migration

1994 • 54 citations

Development of the spatial pattern of retinoic acid receptor-β transcripts in embryonic chick facial primordia

1992 • 51 citations

The murine gene for cellular retinoic acid-binding protein type II. Genomic organization, chromosomal localization, and post-transcriptional regulation by retinoic acid.

1992 • 47 citations

Distribution of TNF alpha-like proteins correlates with some regions of programmed cell death in the chick embryo.

1994 • 45 citations

Alterations in Msx 1 and Msx 2 expression correlate with inhibition of outgrowth of chick facial primordia induced by retinoic acid

1997 • 42 citations

Differential expression of two MSH-related homeobox genes Chox-7 and Chox-8 during chick limb development

1992 • 42 citations

Murine Homeobox-Containing Gene, Msx-1: Analysis of Genomic Organization, Promoter Structure, and Potential Autoregulatory cis-Acting Elements

1994 • 40 citations

The effects of retinoids on cartilage differentiation in micromass cultures of chick facial primordia and the relationship to a specific facial defect

1987 • 33 citations

Expression of the chicken retinoid X receptor-? gene in migrating cranial neural crest cells

1995 • 25 citations

Locally released retinoic acid leads to facial clefts in the chick embryo but does not alter the expression of receptors for fibroblast growth factor.

1995 • 25 citations

Quantitative analysis of the effect of retinoids on facial morphogenesis.

1986 • 25 citations

Characterization of the human MSX-1 promoter and an enhancer responsible for retinoic acid induction.

1994 • 22 citations

Differential expression of homeobox-containing genes Msx-1 and Msx-2 and homeoprotein Msx-2 expression during chick craniofacial development.

1994 • 20 citations

Comparative and functional analysis of the AP2 promoter indicates that conserved octamer and initiator elements are critical for activity

1996 • 20 citations

Influence of epithelial-mesenchymal interaction on the viability of facial mesenchyme in vitro

1989 • 18 citations

Pattern formation in the facial primordia

1988 • 15 citations

Effects of retinoids on chick face development.

1991 • 14 citations