Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate

1974 • 619 citations

Selective effects of actinomycin D on the intracellular distribution of RNA synthesis in tissue culture cells

1963 • 356 citations

An Isotopic Assay for Thymidylate Synthetase^*

1966 • 212 citations

5-Fluorouracil incorporation into human breast carcinoma RNA correlates with cytotoxicity.

1981 • 187 citations

Biochemical determinants of tumor sensitivity to 5-fluorouracil: Ultrasensitive methods for the determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthetase

1979 • 121 citations

5-Fluoro-2'-deoxyuridine incorporation in L1210 DNA.

1981 • 103 citations

Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture.

1982 • 102 citations

Mechanism of action of dichloro-beta-D-ribofuranosylbenzimidazole: effect on in vitro transcription.

1982 • 94 citations

An overview of thymidine

1980 • 87 citations

Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.

1980 • 86 citations

Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil.

1984 • 83 citations

Increased levels of thymidylate synthetase in cells exposed to 5-fluorouracil.

1984 • 80 citations

Mechanism for exclusion of 5-fluorouracil from DNA.

1980 • 71 citations

Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma

1983 • 62 citations

Methods for the complete analysis of 5-fluorouracil metabolites in cell extracts

1981 • 61 citations

Assay of 5-fluorodeoxyuridine 5'-monophosphate deoxyuridine 5'-monophosphate pools following 5-fluorouracil.

1974 • 50 citations

Comparison of two flow cytometric assays for cellular RNA—acridine orange and propidium iodide

1982 • 47 citations

Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity in gastrointestinal tumor cells.

1982 • 45 citations

Defective facilitated diffusion of nucleosides, a primary mechanism of resistance to 5-fluoro-2'-deoxyuridine in the HCT-8 human carcinoma line.

1985 • 40 citations

Use of periodate and methylamine for the quantitation of intracellular 5-fluro-2′-deoxyuridine-5′-monophosphate by high-performance liquid chromatography

1981 • 11 citations

Increased incorporation of 5-fluorodeoxyuridine into DNA of human T-lymphoblastic cell lines.

1984 • 7 citations