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Cardenolide analogs. An explanation for the unusual properties of AY 22241

Data up to Jan 2025

Published1979
Citations33
References19

Total Citations Per Year

Abstract

References (19)

The sodium-potassium adenosine triphosphatase: pharmacological, physiological and biochemical aspects.

1975 • 868 citations

Possible involvement of cardiac Na+, K+-adenosine triphosphatase in the mechanism of action of cardiac glycosides.

1969 • 254 citations

Synthesis and Biological Activity of Semisynthetic Digitalis Analogs

1974 • 74 citations

Improved purification and partial characterization of (Na+, K+)-ATPase from cardiac muscle

1975 • 67 citations

The nature of the transport adenosine triphosphatase-digitalis complex. VII. Characteristics of ouabagenin-Na+,K+-adenosine triphosphatase interaction.

1974 • 56 citations

Structure-activity relationships of cardiotonic steroids for the inhibition of sodium- and potassium-dependent adenosine triphosphatase. 3. Dissociation rate constants of various enzyme-cardiac glycoside complexes formed in the presence of sodium, magnesium, and adenosine triphosphate.

1974 • 44 citations

The influence of the position of attachment of the lactone ring to the steroid nucleus on the action of cardiac glycosides.

1974 • 37 citations

Cardenolide analogs. V. Cardiotonic activity of semisynthetic analogs of digitoxigenin.

1974 • 35 citations

The nature of the transport ATPase—Digitalis complex: III. Rapid binding studies and effects of ligands on the formation and stability of magnesium plus phosphate-induced glycoside—Enzyme complex

1972 • 32 citations

Synthetic cardenolides and related products

1970 • 25 citations

Effects of AY-22,241 (actodigin) on electrical and mechanical activity of cardiac tissues

1975 • 20 citations

Singular effects of a new short acting cardiac glycoside in Purkinje cells

1972 • 19 citations

Structure-Activity Relationships of Cardiotonic Steroids for the Inhibition of Sodium- and Potassium-Dependent Adenosine Triphosphatase

1973 • 16 citations

The relationship between Na+, K+-ATPase inhibition and cardiac glycoside-induced arrhythmia in dogs

1977 • 13 citations

Rapidly reversible inhibition of frog muscle sodium pump caused by cardiotonic steroids with modified lactone rings

1974 • 10 citations

Reversible inhibition of (Na+ + K+)-ATPase with a cardiac glycoside

1975 • 10 citations

Effects of actodigin on the heart

1977 • 6 citations

N<scp>a</scp>, K‐ACTIVATED ATP<scp>ase</scp> ACTIVITY DURING AND AFTER ARRHYTHMIC RESPONSE TO AY‐22–241 IN THE CANINE HEART*

1974 • 6 citations

A comparison of actodigin and ouabain in cats.

1977 • 5 citations

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Cardenolide analogs. An explanation for the unusual properties of AY 22241 (1979) – European Journal of Pharmacology | Metascience Observatory Explorer