TRAF2 and TRAF3 Signal Adapters Act Cooperatively to Control the Maturation and Survival Signals Delivered to B Cells by the BAFF Receptor

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Inducible Gene Targeting in Mice

1995 • 1,897 citations

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

2000 • 1,596 citations

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

1999 • 1,464 citations

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

2001 • 1,333 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

2007 • 1,166 citations

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

1997 • 1,091 citations

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

2001 • 1,048 citations

TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40

1995 • 1,046 citations

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

2007 • 1,028 citations

Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

2007 • 974 citations

IL-7 is critical for homeostatic proliferation and survival of naïve T cells

2001 • 940 citations

Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma

2007 • 925 citations

Excess BAFF Rescues Self-Reactive B Cells from Peripheral Deletion and Allows Them to Enter Forbidden Follicular and Marginal Zone Niches

2004 • 711 citations

B lymphocyte-specific, Cre-mediated mutagenesis in mice

1997 • 696 citations

BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells

2002 • 674 citations

Tissue- and site-specific DNA recombination in transgenic mice.

1992 • 651 citations

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

2000 • 579 citations

Reduced Competitiveness of Autoantigen-Engaged B Cells due to Increased Dependence on BAFF

2004 • 564 citations

Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1997 • 552 citations

Regulation of the T-Independent Humoral Response by TACI

2001 • 513 citations

BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2

2002 • 468 citations

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

2002 • 453 citations

Regulation of the NF-κB-inducing Kinase by Tumor Necrosis Factor Receptor-associated Factor 3-induced Degradation

2004 • 449 citations

Activation and accumulation of B cells in TACI-deficient mice

2001 • 409 citations

Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population

2000 • 393 citations

TNF Family Member B Cell-Activating Factor (BAFF) Receptor-Dependent and -Independent Roles for BAFF in B Cell Physiology

2004 • 365 citations

Cutting Edge: BLyS Enables Survival of Transitional and Mature B Cells Through Distinct Mediators

2002 • 309 citations

B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling

2007 • 275 citations

B Cell-Activating Factor Belonging to the TNF Family Acts through Separate Receptors to Support B Cell Survival and T Cell-Independent Antibody Formation

2004 • 249 citations

Maturation of Marginal Zone and Follicular B Cells Requires B Cell Activating Factor of the Tumor Necrosis Factor Family and Is Independent of B Cell Maturation Antigen

2001 • 238 citations

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs

2005 • 232 citations

How αβ T cells deal with induced TCRα ablation

2001 • 224 citations

TRAF2 Differentially Regulates the Canonical and Noncanonical Pathways of NF-κB Activation in Mature B Cells

2004 • 211 citations

Tumor Necrosis Factor Receptor-Associated Factor 3 Is a Critical Regulator of B Cell Homeostasis in Secondary Lymphoid Organs

2007 • 198 citations

Iκb Kinase α Is Essential for Mature B Cell Development and Function

2001 • 186 citations

Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia (aly) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase

2000 • 164 citations

Rescue of TRAF3-null mice by p100 NF-κB deficiency

2006 • 164 citations

TNFR-Associated Factor-3 Is Associated With BAFF-R and Negatively Regulates BAFF-R-Mediated NF-κB Activation and IL-10 Production

2002 • 144 citations

An Atypical Tumor Necrosis Factor (TNF) Receptor-associated Factor-binding Motif of B Cell-activating Factor Belonging to the TNF Family (BAFF) Receptor Mediates Induction of the Noncanonical NF-κB Signaling Pathway

2005 • 111 citations

Complete structural characterisation of the mammalian and Drosophila TRAF genes: implications for TRAF evolution and the role of RING finger splice variants

2000 • 87 citations

TNF受容体(TNFR)関連因子(TRAF)3はTRAF結合性TNFRによる非定型的NFκB経路のTRAF2/5介在性活性化の阻害物質として働く

2005 • 58 citations

Analysis of an Ethylnitrosourea-generated Mouse Mutation Defines a Cell Intrinsic Role of Nuclear Factor κB2 in Regulating Circulating B Cell Numbers

2002 • 52 citations