LIF/STAT3 Signaling Fails to Maintain Self‐Renewal of Human Embryonic Stem Cells

Embryonic Stem Cell Lines Derived from Human Blastocysts

1998 • 15,541 citations

Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells

2003 • 3,230 citations

The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells

2003 • 3,179 citations

Stat3 as an Oncogene

1999 • 2,770 citations

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

2000 • 2,733 citations

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

1994 • 2,037 citations

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1988 • 2,004 citations

Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

1995 • 1,960 citations

Feeder-free growth of undifferentiated human embryonic stem cells

2001 • 1,860 citations

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1988 • 1,848 citations

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

1998 • 1,518 citations

Clonally Derived Human Embryonic Stem Cell Lines Maintain Pluripotency and Proliferative Potential for Prolonged Periods of Culture

2000 • 1,488 citations

<scp>gp</scp>130 AND THE INTERLEUKIN-6 FAMILY OF CYTOKINES

1997 • 1,468 citations

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

1993 • 1,395 citations

Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells

2000 • 1,132 citations

BMP4 initiates human embryonic stem cell differentiation to trophoblast

2002 • 1,107 citations

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

1995 • 992 citations

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

1999 • 885 citations

An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo

1989 • 596 citations

RETRACTED: Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death

1999 • 443 citations

Essential role of STAT3 for embryonic stem cell pluripotency

1999 • 404 citations

Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines

2001 • 264 citations

Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes

1991 • 262 citations

Three Monoclonal Antibodies Defining Distinct Differentiation Antigens Associated with Different High Molecular Weight Polypeptides on the Surface of Human Embryonal Carcinoma Cells

1984 • 232 citations

Leukemia Inhibitory Factor–dependent Transcriptional Activation in Embryonic Stem Cells

1997 • 217 citations

Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential

2001 • 111 citations

Hypothalamic-Pituitary Cytokine Network

2003 • 75 citations

Cross-species receptor binding characteristics of human and mouse leukemia inhibitory factor suggest a complex binding interaction.

1994 • 44 citations

The Unusual Species Cross-reactivity of the Leukemia Inhibitory Factor Receptor α-Chain Is Determined Primarily by the Immunoglobulin-like Domain

1997 • 42 citations

The c-Myc Oncoprotein Interacts with Bcr

2003 • 22 citations