Sample sizes for long-term medical trial with time-dependent dropout and event rates

Planning the size and duration of a clinical trial studying the time to some critical event

1974 • 287 citations

Statistical design considerations in the NHLI multiple risk factor intervention trial (MRFIT)

1977 • 141 citations

Sample sizes for medical trials with special reference to long-term therapy

1968 • 134 citations

The determination of sample size in treatment-control comparisons for chronic disease studies in which drop-out or non-adherence is a problem

1967 • 52 citations

Planning the duration of long-term survival time studies designed for accrual by cohorts

1971 • 46 citations