Cruel antibody fictions! Cellular antigen enumeration by ‘saturation’ binding

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Handbook of experimental immunology

1987 • 680 citations

The kinetics of antibody binding to membrane antigens in solution and at the cell surface

1980 • 568 citations

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

1983 • 464 citations

[13] The meaning of scatchard and hill plots

1978 • 312 citations

Cytofluorometric quantification of cell-surface antigens by indirect immunofluorescence using monoclonal antibodies

1985 • 192 citations

Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation.

1989 • 159 citations

Receptor clustering on a cell surface. I. theory of receptor cross-linking by ligands bearing two chemically identical functional groups

1980 • 150 citations

The implications of subunit interactions for the structure of the T cell receptor‐CD3 complex

1990 • 130 citations

Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex.

1991 • 129 citations

Theory of Equilibrium Binding of Symmetric Bivalent Haptens to Cell Surface Antibody: Application to Histamine Release from Basophils

1978 • 125 citations

The interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. I. Analysis of the mechanism of binding.

1984 • 115 citations

T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor

1991 • 113 citations

Structure of the T-cell antigen receptor: evidence for two CD3 epsilon subunits in the T-cell receptor-CD3 complex.

1990 • 110 citations

Interaction of divalent antibody with cell surface antigens

1979 • 91 citations

Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains.

1994 • 90 citations

The binding of monoclonal antibodies to cell-surface molecules. A quantitative analysis with immunoglobulin G against two alloantigenic determinants of the human transplantation antigen HLA-A2

1983 • 56 citations

A theory of bivalent antibody-bivalent hapten interactions

1973 • 47 citations

Flow cytometry: A novel approach for the quantitative analysis of receptor-ligand interactions on surfaces of living cells

1980 • 46 citations

Compared TCR and CD3 epsilon expression on alpha beta and gamma delta T cells. Evidence for the association of two TCR heterodimers with three CD3 epsilon chains in the TCR/CD3 complex.

1995 • 44 citations

Pre-TCR/CD3 and TCR/CD3 complexes: decamers with differential signalling properties?

1997 • 41 citations

Effect of antibody valency on interaction with cell-surface expressed HIV-1 and viral neutralization.

1994 • 35 citations

A Humanized, Bispecific Immunoadhesin-Antibody that Retargets CD3+ Effectors to Kill HIV-1-Infected Cells

1995 • 35 citations

The kinetics of bivalent ligand-bivalent receptor aggregation: Ring formation and the breakdown of the equivalent site approximation

1995 • 31 citations

A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells.

1994 • 30 citations

Interpretation of Scatchard plots for aggregating receptor systems

1992 • 30 citations

Thermodynamics of antibody-antigen reactions. 2. The binding of bivalent synthetic random coil antigens to antibodies having different antigen precipitating properties

1977 • 29 citations

Bivalent hapten-antibody interactions—I, a comparison of water soluble and water insoluble bivalent haptens

1975 • 19 citations

Optimization of Radioligand Binding and Radioimmuno Assays

1996 • 5 citations

Ring formation in divalent-receptor-divalent-ligand interaction: Pseudocooperative shapes of scatchard plots

1988 • 3 citations