Ezetimibe and Simvastatin Reduce Inflammation, Disease Activity, and Aortic Stiffness and Improve Endothelial Function in Rheumatoid Arthritis

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

2002 • 6,780 citations

Modified disease activity scores that include twenty-eight-joint counts development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

1995 • 5,929 citations

Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

1999 • 2,131 citations

Long-Term Follow-Up of Patients With Mild Coronary Artery Disease and Endothelial Dysfunction

2000 • 2,076 citations

Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease

1994 • 1,697 citations

Measurement of C-Reactive Protein for the Targeting of Statin Therapy in the Primary Prevention of Acute Coronary Events

2001 • 1,537 citations

Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Infliximab, a Chimeric Monoclonal Antibody to Tumor Necrosis Factor-α, in Patients With Moderate-to-Severe Heart Failure

2003 • 1,504 citations

Long-Term Effects of Pravastatin on Plasma Concentration of C-reactive Protein

1999 • 1,488 citations

Inflammation, Pravastatin, and the Risk of Coronary Events After Myocardial Infarction in Patients With Average Cholesterol Levels

1998 • 1,398 citations

The mortality of rheumatoid arthritis

1994 • 1,323 citations

High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors

2001 • 1,296 citations

High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors

2001 • 1,040 citations

Simvastatin, an HMG–Coenzyme A Reductase Inhibitor, Improves Endothelial Function Within 1 Month

1997 • 968 citations

Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis

1998 • 920 citations

Immune Mechanisms in Atherosclerosis

2001 • 852 citations

Immune mechanisms in atherosclerosis.

1989 • 827 citations

Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

2004 • 818 citations

Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events

2001 • 783 citations

Effect of Ezetimibe Coadministered With Atorvastatin in 628 Patients With Primary Hypercholesterolemia

2003 • 683 citations

Direct Interaction of Endothelial Nitric-oxide Synthase and Caveolin-1 Inhibits Synthase Activity

1997 • 647 citations

Anti–Tumor Necrosis Factor-α Treatment Improves Endothelial Function in Patients With Rheumatoid Arthritis

2002 • 578 citations

Single LDL Apheresis Improves Endothelium-Dependent Vasodilatation in Hypercholesterolemic Humans

1997 • 550 citations

Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascular events in patients with rheumatoid arthritis.

2005 • 532 citations

Simvastatin Versus Ezetimibe

2005 • 425 citations

Antisense to LOX-1 Inhibits Oxidized LDL–Mediated Upregulation of Monocyte Chemoattractant Protein-1 and Monocyte Adhesion to Human Coronary Artery Endothelial Cells

2000 • 413 citations

Rheumatoid Arthritis Is Associated With Increased Aortic Pulse-Wave Velocity, Which Is Reduced by Anti–Tumor Necrosis Factor-α Therapy

2006 • 407 citations

Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase

1999 • 396 citations

Low-density lipoproteins inhibit endothelium-dependent relaxation in rabbit aorta

1987 • 310 citations

Arterial Stiffness in Chronic Inflammatory Diseases

2005 • 299 citations

Ciprofibrate Therapy Improves Endothelial Function and Reduces Postprandial Lipemia and Oxidative Stress in Type 2 Diabetes Mellitus

2000 • 225 citations

Impaired Responsiveness to NO in Newly Diagnosed Patients With Rheumatoid Arthritis

2002 • 219 citations

Beyond the Laboratory

2004 • 198 citations

Effects of HMG-CoA Reductase Inhibitors on Endothelial Function

2004 • 171 citations

Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for ‘pleiotropic’ functions of statin therapy

2006 • 146 citations

LOX-1, an Oxidized LDL Endothelial Receptor, Induces CD40/CD40L Signaling in Human Coronary Artery Endothelial Cells

2003 • 144 citations

Effect of coadministration of ezetimibe and simvastatin on high-sensitivity C-reactive protein

2003 • 127 citations

Endothelial dysfunction in young patients with long-term rheumatoid arthritis and low disease activity

2003 • 115 citations

Major Clinical Trials of Hypertension

2005 • 97 citations

Intracellular free radical production in synovial T lymphocytes from patients with rheumatoid arthritis

2005 • 77 citations

Effects of fenofibrate on lipoproteins, vasomotor function, and serological markers of inflammation, plaque stabilization, and hemostasis

2004 • 64 citations

Increased stiffness of the abdominal aorta in women with rheumatoid arthritis

2005 • 41 citations

The effect of simvastatin, ezetimibe and their combination on the lipid profile, arterial stiffness and inflammatory markers

2007 • 40 citations

Pseudoaneurysms of the Ascending Aorta Demonstrated With “Motion-Free” Multislice Computed Tomography

2004 • 35 citations

Systemic Acyl-CoA:Cholesterol Acyltransferase Inhibition Reduces Inflammation and Improves Vascular Function in Hypercholesterolemia

2005 • 22 citations

Deleted Work

1955 • 0 citations