Unscheduled DNA synthesis in spermatogenic cells of mice treated in vivo with the indirect alkylating agents cyclophosphamide and mitomen

A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal

1956 • 993 citations

Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium

1956 • 952 citations

AUTORADIOGRAPHIC STUDY OF DNA SYNTHESIS AND THE CELL CYCLE IN SPERMATOGONIA AND SPERMATOCYTES OF MOUSE TESTIS USING TRITIATED THYMIDINE

1962 • 361 citations

Induction of dominant lethal mutations by alkylating agents in male mice

1968 • 212 citations

Enzymatic metabolism of cyclophosphamide and nicotine and production of a toxic cyclophosphamide metabolite.

1972 • 183 citations

A Review of Cyclophosphamide.

1975 • 173 citations

Metabolism of cyclophosphamide by rat hepatic microsomes.

1971 • 157 citations

Unscheduled DNA Synthesis in the Germ Cells of Male Mice Exposed In Vivo to the Chemical Mutagen Ethyl Methanesulfonate

1974 • 147 citations

Activation of cyclophosphamide in man and animals

1971 • 142 citations

Differential spermatogenic response of mice to the induction of mutations by antineoplastic drugs

1974 • 125 citations

Therapeutic efficacy of cyclophosphamide as a function of its metabolism.

1972 • 120 citations

Ethyl methanesulfonate-induced chromosome breakage in the mouse

1968 • 117 citations

A Review of Cyclophosphamide

1975 • 108 citations

Radiation-initiated DNA synthesis in spermatogenic cells of the mouse

1971 • 93 citations

Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl-, ethyl-, propyl-, and isopropyl methanesulfonate

1976 • 87 citations

A study of unscheduled DNA synthesis induced by X-rays in the germ cells of male mice

1978 • 85 citations

Induction of translocations by cyclophosphamide in different germ cell stages of male mice: Cytological characterization and transmission

1975 • 78 citations

Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide.

1973 • 78 citations

“Unscheduled” DNA synthesis in human germ cells following UV irradiation

1971 • 72 citations

Die mutagene Wirkung von Endoxan bei der Maus

1966 • 55 citations

The effect of phenobarbital on cyclophosphamide antitumor activity.

1976 • 44 citations

Molecular and cellular repair processes

1972 • 41 citations

Unscheduled synthesis of DNA during mammalian spermatogenesis in response to UV irradiation

1973 • 40 citations

Effects of nitrogen mustard and cyclophosphamide upon the synthesis of DNA in vivo and in cell-free preparations.

1969 • 40 citations

The in vivo biosynthesis of DNA, RNA, and proteins by mouse embryos after a teratogenic dose of cyclophosphamide

1972 • 21 citations

Studies on Carcinostatic Substances. XXVIII. Activation of the Derivatives of 2-Chloroethylamine with Latent Activity

1960 • 9 citations

The mode of action of nitrogen mustard N-oxide.

1959 • 3 citations

Nitromin content in the circulating blood and the urine.

1959 • 3 citations