Exonucleolytic proofreading of leading and lagging strand DNA replication errors.

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Kinetic amplification of enzyme discrimination

1975 • 742 citations

Simian virus 40 DNA replication in vitro.

1984 • 562 citations

Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

1988 • 495 citations

EUKARYOTIC CHROMOSOME REPLICATION

1975 • 455 citations

Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin

1990 • 430 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA

1988 • 395 citations

A third essential DNA polymerase in S. cerevisiae

1990 • 360 citations

Heteroduplex repair in extracts of human HeLa cells

1991 • 355 citations

The in vitro replication of DNA containing the SV40 origin.

1990 • 268 citations

Initiation of SV40 DNA replication in vivo: Location and structure of 5′ ends of DNA synthesized in the ori region

1982 • 257 citations

A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzyme.

1984 • 246 citations

Identification of cellular proteins required for simian virus 40 DNA replication

1989 • 238 citations

Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication.

1985 • 206 citations

SV40 DNA replication.

1988 • 184 citations

The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.

1990 • 169 citations

Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.

1979 • 167 citations

Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation.

1979 • 165 citations

Purification and characterization of two new high molecular weight forms of DNA polymerase .delta.

1986 • 153 citations

On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis.

1979 • 151 citations

Exonucleolytic proofreading

1988 • 133 citations

Studies on the mutator gene, mutT of Escherichia coli. Molecular cloning of the gene, purification of the gene product, and identification of a novel nucleoside triphosphatase.

1988 • 130 citations

Revised nomenclature for eukaryotic DNA polymerases

1990 • 120 citations

A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication.

1989 • 120 citations

Properties of DNA polymerases δ and ϵ, and their roles in eukaryotic DNA replication

1991 • 116 citations

Exonucleolytic proofreading by calf thymus DNA polymerase delta.

1987 • 111 citations

Inequality in mutation rates of the two strands of DNA

1987 • 109 citations

A cryptic proofreading 3'----5' exonuclease associated with the polymerase subunit of the DNA polymerase-primase from Drosophila melanogaster.

1987 • 109 citations

On the fidelity of DNA replication. Effect of the next nucleotide on proofreading.

1981 • 107 citations

Fidelity of a human cell DNA replication complex.

1988 • 93 citations

Selective inhibition of the 3' to 5' exonuclease activity associated with DNA polymerases: a mechanism of mutagenesis

1977 • 93 citations

Contribution of 3′ → 5′ exonuclease activity of DNA polymerase III holoenzyme from Escherichia coli to specificity

1983 • 88 citations

Simian Virus 40 DNA Replication In Vitro: Specificity of Initiation and Evidence for Bidirectional Replication

1985 • 84 citations

Translational control of SV40 T antigen expressed from the adenovirus late promoter

1983 • 79 citations

The interaction of DNA polymerase III and the product of the Escherichia coli mutator gene, mutD.

1984 • 73 citations

Mechanism of selective inhibition of 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5'-monophosphates

1978 • 68 citations

Escherichia coli mutT mutator effect during in vitro DNA synthesis. Enhanced A.G replicational errors.

1987 • 57 citations

Hydrolysis of 3'-terminal mispairs in vitro by the 3' .fwdarw. 5' exonuclease of DNA polymerase .delta. permits subsequent extension by DNA polymerase .alpha.

1990 • 51 citations

Do DNA polymerases δ and α act coordinately as leading and lagging strand replicases?

1988 • 45 citations

Fidelity of DNA synthesis in a mammalian in vitro replication system.

1988 • 32 citations

DNA polymerase α and models for proofreading

1985 • 22 citations