Parameter and structure-activity data bases: management for maximum utility.

Substituent constants for correlation analysis in chemistry and biology

1979 • 2,909 citations

Substituent Constants for Correlation Analysis in Chemistry and Biology.

1980 • 2,780 citations

Aromatic substituent constants for structure-activity correlations

1973 • 1,189 citations

Rates and equilibria of organic reactions

1963 • 946 citations

A Mathematical Contribution to Structure-Activity Studies

1964 • 913 citations

Linear Relationships between Lipophilic Character and Biological Activity of Drugs

1972 • 444 citations

Physical organic Chemistry

1987 • 382 citations

Development and Application of New Steric Substituent Parameters in Drug Design

1976 • 322 citations

Calculation of hydrophobic constant (log P) from .pi. and f constants

1975 • 291 citations

Hydrophobic Fragmental Constant

2016 • 223 citations

Strategy in drug design. Cluster anlysis as an aid in the selection of substituents

1973 • 148 citations

Correlation of serum binding of penicillins with partition coefficients

1967 • 118 citations

α-Chymotrypsin: A Case Study of Substituent Constants and Regression Analysis in Enzymic Structure—Activity Relationships

1970 • 110 citations

The Use of Substituent Constants in the Analysis of the Structure-Activity Relationship in Penicillin Derivatives

1964 • 92 citations

Thiopurine methyltransferase. Aromatic thiol substrates and inhibition by benzoic acid derivatives.

1983 • 90 citations

The octanol–water partition coefficient of aromatic solutes: the effect of electronic interactions, alkyl chains, hydrogen bonds, and ortho-substitution

1983 • 75 citations

The Wiswesser line-formula chemical notation

1968 • 68 citations

The Role of Hydrophobic Bonding in the Binding of Organic Compounds by Bovine Hemoglobin^*

1966 • 63 citations

The wiswesser line-formula chemical notation

1968 • 63 citations

Structure-activity relationships in membrane-perturbing agents. Hemolytic, narcotic, and antibacterial compounds.

1971 • 59 citations

Confidence interval estimators for parameters associated with quantitative structure-activity relationships

1980 • 44 citations

The inhibition of alcohol dehydrogenase in vitro and in isolated hepatocytes by 4-substituted pyrazoles

1983 • 43 citations

The use of crystallography, graphics, and quantitative structure-activity relationships in the analysis of the papain hydrolysis of X-phenyl hippurates

1982 • 40 citations

A Hammett-Taft Polar-Steric Equation for the Saponification Rates of m- and p-Substituted Alkyl Benzoates¹

1961 • 33 citations

Computerized Management of Structure-Activity Data. I. Multivariate Analysis of Biological Data

1974 • 16 citations

The Extrathermodynamic Structure-Activity Correlations

1974 • 11 citations

The Use of Quantitative Structure-Activity Relationships as an Aid to the Interpretation of Blood Levels in Gases of Fatal Barbiturate Poisoning

1981 • 10 citations

Comparison of quantitative structure-activity relationships of the inhibition of leukemia cells in culture with the inhibition of dihydrofolate reductase from leukemia cells and other cell types

1982 • 10 citations

Computer-Generated Substructure Codes (Bit Screens)

1971 • 8 citations