Dopaminergic hypersensitivity and cholinergic hypofunction in the pathophysiology of tardive dyskinesia

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

A CHOLINERGIC-ADRENERGIC HYPOTHESIS OF MANIA AND DEPRESSION

1972 • 1,077 citations

The Pharmacology of Tardive Dyskinesias

1973 • 512 citations

L-dopa therapy in Parkinson's disease: a critical review of nine years' experience.

1969 • 403 citations

Cholinergic-Anticholinergic Antagonism in Parkinsonism

1967 • 337 citations

Regular Induction of Hypomania by L-Dopa in “Bipolar” Manic-depressive Patients

1971 • 257 citations

Tardive Dyskinesia in Patients Treated with Major Neuroleptics: A Review of the Literature

1968 • 235 citations

Reversible and irreversible dyskinesia after treatment with perphenazine, chlorpromazine, reserpine and electroconvulsive therapy

1960 • 228 citations

Persistent Dyskinesia

1973 • 222 citations

On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats.

1972 • 202 citations

Cholinergic Mechanism in Brain inhibiting Amphetamine‐induced Stereotyped Behaviour

1968 • 187 citations

NEUROPATHOLOGICAL INVESTIGATION OF 28 BRAINS FROM PATIENTS WITH DYSKINESIA

1970 • 170 citations

Central Effects of Anticholinergic Drugs Measured by the Apomorphine Gnawing Test in Mice

1969 • 155 citations

Central cholinergic‐anticholinergic antagonism in Huntington's chorea

1972 • 150 citations

A Pharmacologic Analysis of Huntington’s Chorea

1970 • 146 citations

Treatment of Tardive Dyskinesia

1972 • 140 citations

Studies of Alpha-methyl-para-tyrosine, L-dopa, and L-tryptophan in Depression and Mania

1971 • 137 citations

THE PRESENT STATUS OF PSYCHOTROPIC DRUGS

1966 • 137 citations

The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine (clozapine).

1971 • 136 citations

Das klinische Wirkungsbild von Clozapin: (Untersuchung mit dem AMP-System)

1971 • 129 citations

Behavioral effects of l-Dopa in schizophrenic patients

1973 • 119 citations

Cholinergic and dopaminergic mechanisms in Huntington's chorea

1971 • 112 citations

Treatment of Tardive Dyskinesia

1972 • 110 citations

Potentiation of phenothiazines by?-methyltyrosine in treatment of chronic schizophrenia

1972 • 86 citations

Implications of Amphetamine-Induced Stereotyped Behavior as a Model for Tardive Dyskinesias

1972 • 84 citations

Stereotypic and anticataleptic activities of amphetamine after intracerebral injections

1972 • 76 citations

The long-term effect of perphenazine enanthate on the rat brain. Some metabolic and anatomical observations

1973 • 73 citations

Observations on the effect of levodopa on tardive lingual-facial-buccal dyskinesia

1971 • 69 citations

COMBINED NITOMAN®-PIMOZIDE® TREATMENT OF HUNTINGTON'S CHOREA AND OTHER HYPERKINETIC SYNDROMES

1970 • 60 citations

Levodopa in the Treatment of Parkinsonism

1971 • 48 citations

TREATMENT OF DRUG-INDUCED DYSKINESIAS

1970 • 48 citations

The effect of l-dopa and (+)-amphetamine on the locomotor activity after pimozide and phenoxybenzamine

1972 • 45 citations

Interactions between central cholinergic agents and amphetamine in mice

1965 • 44 citations

Dopamine, extrapyramidal system, and psychomotor function.

1972 • 43 citations

Prevention and Management of Tardive Dyskinesia

1972 • 39 citations

Tardive Dyskinesia: Its Relation to Neuroleptic and Antiparkinson Drugs

1972 • 34 citations

Reversal by Levodopa of Cholinergic Hypersensitivity in Parkinson's Disease

1971 • 32 citations

Levodopa, Involuntary Movements and Fusaric Acid

1971 • 25 citations

Integrated effect of psychotropic drugs on the balance of cholino-, adreno-, and serotoninergic processes in the brain as a basis of their gross behavioral and therapeutic actions.

1967 • 20 citations

“Paradoxical” stereotyped activity of reserpinized rats

1968 • 15 citations

Pharmacological evidence for a cholinergic mechanism in brain involved in a special stereotyped behaviour of reserpinized rats.

1968 • 15 citations

[Effect of dioxyphenylalanine (L-DOPA) on extrapyramidal motoric hyperkineses after prolonged neuroleptic therapy].

1970 • 11 citations