PHARMACOLOGICAL APPROACHES TO THE CHARACTERIZATION OF β-ADRENORECEPTOR POPULATIONS IN TISSUES

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Simultaneous determination of beta-1 and beta-2-adrenergic receptors in tissues containing both receptor subtypes.

1979 • 418 citations

The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors

1965 • 342 citations

The pharmacological specificity of beta-1 and beta-2 adrenergic receptors in rat heart and lung in vitro.

1979 • 243 citations

Evidence that ICI 118, 551 is a potent, highly beta2-selective adrenoceptor antagonist and can be used to characterize beta-adrenoceptor populations in tissues

1980 • 210 citations

Differential distribution of beta-1 and beta-2 adrenergic receptors in cat and guinea-pig heart.

1980 • 156 citations

The importance of choice of agonist in studies designed to predict ? 2:? 1 adrenoceptor selectivity of antagonists from pA2 values on guinea-pig trachea and atria

1979 • 130 citations

A study designed to explore the hypothesis that beta-1 adrenoceptors are "innervated" receptors and beta-2 adrenoceptors are "hormonal" receptors.

1981 • 99 citations

Pharmacological characterization of receptors: its relation to radioligand-binding studies.

1978 • 92 citations

Subclassification of beta-adrenergic receptors in cultured rat cardiac myoblasts and fibroblasts.

1980 • 72 citations

Evidence that the efficacy (intrinsic activity) of fenoterol is higher than that of salbutamol on β-adrenoceptors in guinea-pig trachea

1978 • 49 citations

pA2values of selective β-adrenoceptor antagonists on isolated atria demonstrate a species difference in the β-adrenoceptor populations mediating chronotropic responses in cat and guinea-pig

1979 • 41 citations

Postsynaptic Adrenergic Receptor Mechanisms in Vascular Smooth Muscle1

2015 • 36 citations

Salbutamol: agonistic and antagonistic activity at β-adrenoceptor sites

1973 • 26 citations