Do neutrophils mediate the phenomenon of stunned myocardium?

The stunned myocardium: prolonged, postischemic ventricular dysfunction.

1982 • 2,825 citations

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

1983 • 1,168 citations

Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog.

1983 • 845 citations

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

1988 • 691 citations

Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs.

1984 • 468 citations

Effect of a transient period of ischemia on myocardial cells. II. Fine structure during the first few minutes of reflow.

1974 • 434 citations

Mitochondrial Production of Superoxide Radical and Hydrogen Peroxide

1977 • 415 citations

The Histopathologic Evolution of Myocardial Infarction

1978 • 408 citations

Superoxide dismutase plus catalase improve contractile function in the canine model of the "stunned myocardium".

1986 • 360 citations

Superoxide dismutase plus catalase enhances the efficacy of hypothermic cardioplegia to protect the globally ischemic, reperfused heart

1982 • 355 citations

Oxygen-derived free radicals and postischemic myocardial dysfunction (“stunned myocardium”)

1988 • 349 citations

Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischemia.

1985 • 324 citations

Free radicals and myocardial ischemia and reperfusion injury.

1987 • 307 citations

Depression of regional blood flow and wall thickening after brief coronary occlusions

1978 • 305 citations

Prolonged derangements of canine myocardial purine metabolism after a brief coronary artery occlusion not associated with anatomic evidence of necrosis

1980 • 257 citations

Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog.

1987 • 231 citations

Hydrogen peroxide and hydroxyl radical mediation of activated leukocyte depression of cardiac sarcoplasmic reticulum. Participation of the cyclooxygenase pathway.

1983 • 222 citations

Time course and determinants of recovery of function after reversible ischemia in conscious dogs

1988 • 218 citations

Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs

1986 • 205 citations

Accumulation of polymorphonuclear leukocytes during 3-h experimental myocardial ischemia

1986 • 204 citations

Altered myocardial states

1989 • 187 citations

Prostacyclin protects ischemic reperfused myocardium in the dog by inhibition of neutrophil activation

1987 • 159 citations

The effect of streptokinase on intramyocardial hemorrhage, infarct size, and the no-reflow phenomenon during coronary reperfusion.

1984 • 156 citations

Myocardial neutrophil accumulation during reperfusion after reversible or irreversible ischemic injury

1988 • 142 citations

Postischemic Myocardial "Stunning": A Clinically Relevant Phenomenon

1988 • 133 citations

Dose-dependent effects of short-term methylprednisolone on myocardial infarct extent, scar formation, and ventricular function.

1983 • 126 citations

Scar thinning due to ibuprofen administration after experimental myocardial infarction

1983 • 120 citations

Indomethacin-induced scar thinning after experimental myocardial infarction.

1983 • 99 citations

Influence of exogenously generated oxidant species on myocardial function

1986 • 90 citations

Effect of prazosin treatment on carbohydrate and lipoprotein metabolism in patients with hypertension

1989 • 74 citations

Influence of neutrophil depletion on myocardial function and flow after reversible ischemia

1989 • 68 citations

Neutrophil depletion does not prevent myocardial dysfunction after brief coronary occlusion

1989 • 56 citations

Activated neutrophils depress myocardial function in the perfused rabbit heart.

1991 • 16 citations

Superoxide dismutase does not cause scar thinning after myocardial infarction

1987 • 8 citations