Growth factors in the uterus: steroidal regulation and biological actions

Angiogenic Factors

1987 • 3,702 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Preimplantation embryo development in vitro: cooperative interactions among embryos and role of growth factors.

1990 • 685 citations

Apparent role of the macrophage growth factor, CSF-1, in placental development

1987 • 506 citations

Proteolytic degradation of extracellular matrix in tumor invasion

1987 • 484 citations

Cloning and Expression of a Developmentally Regulated Protein That Induces Mitogenic and Neurite Outgrowth Activity

1990 • 468 citations

Tissue Distribution of Insulin-Like Growth Factor I and II Messenger Ribonucleic Acid in the Adult Rat*

1987 • 418 citations

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

1987 • 416 citations

Purification and initial characterization of a type beta transforming growth factor from human placenta.

1983 • 409 citations

Regulation of epidermal growth factor receptor by estrogen.

1985 • 379 citations

An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors.

1989 • 369 citations

The fibroblast growth factor family: Structural and biological properties

1989 • 362 citations

Estrogen Induces Insulin—Like Growth Factor—I Expression in the Rat Uterus

1987 • 353 citations

Pattern of interleukin 6 gene expression in vivo suggests a role for this cytokine in angiogenesis.

1990 • 350 citations

Fibroblast growth factor: Structural and biological properties

1987 • 334 citations

The functions of uterine secretions

1988 • 325 citations

Uterine Insulin-Like Growth Factor-1: Regulation of Expression and Its Role in Estrogen-Induced Uterine Proliferation*

1990 • 314 citations

Regulation of colony-stimulating factor 1 during pregnancy.

1986 • 314 citations

Menstruation in intraocular endometrial transplants in the Rhesus monkey

1978 • 306 citations

Characterization of the Insulin and Somatomedin-C Receptors in Human Placental Cell Membranes

1974 • 301 citations

Estrogen Regulates the Synthesis of Epidermal Growth Factor in Mouse Uterine Epithelial Cells

1990 • 288 citations

The immunostimulatory effect of T cells and T cell lymphokines on murine fetally derived placental cells.

1987 • 282 citations

Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development.

1989 • 280 citations

Influence of Estrogens on Mouse Uterine Epidermal Growth Factor Precursor Protein and Messenger Ribonucleic Acid

1988 • 273 citations

Cytokine-induced production of IFN-beta 2/IL-6 by freshly explanted human endometrial stromal cells. Modulation by estradiol-17 beta.

1989 • 260 citations

Angiogenesis in reproductive tissues

1986 • 258 citations

Cytokine networks in the uteroplacental unit: Macrophages as pivotal regulatory cells

1989 • 240 citations

Aortic endothelial cells synthesize basic fibroblast growth factor which remains cell associated and platelet‐derived growth factor‐like protein which is secreted

1987 • 229 citations

The ontogeny of epidermal growth factor receptors during mouse development

1984 • 213 citations

A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: Purification and N-terminal amino acid sequence

1989 • 211 citations

Expression of the c-fms proto-oncogene and of the cytokine, CSF-1, during mouse embryogenesis

1989 • 187 citations

FACTORS FROM MOUSE TISSUES STIMULATING COLONY GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1971 • 187 citations

Tissue and cell type-specific expression of two human c-onc genes

1983 • 182 citations

Estrogen induction of growth factors specific for hormone-responsive mammary, pituitary, and kidney tumor cells.

1978 • 181 citations

Transcription of c-onc Genes c-ras^Ki and c-fms During Mouse Development

1983 • 173 citations

Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion.

1983 • 171 citations

Estrogen Regulation of Epidermal Growth Factor Receptor Messenger Ribonucleic Acid

1988 • 168 citations

Expression of Rat Transforming Growth Factor Alpha mRNA during Development Occurs Predominantly in the Maternal Decidua

1987 • 162 citations

Proliferation of Mouse Uterine Epithelial Cellsin Vitro

1986 • 156 citations

Functional EGF receptors are present on mouse embryo tissues

1981 • 154 citations

Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines.

1986 • 154 citations

Porcine Insulin-Like Growth Factor-I (pIGF-I): Complementary Deoxyribonucleic Acid Cloning and Uterine Expression of Messenger Ribonucleic Acid Encoding Evolutionary Conserved IGF-I Peptides*

1988 • 136 citations

An Autocrine/Paracrine Role forInsulin-Like Growth Factors inthe Regulation ofHuman Placental Growth*

1986 • 133 citations

Insulin-like growth factor 2 and short-range stimulatory loops in control of human placental growth.

1989 • 130 citations

Hormonal Regulation of Insulin-Like Growth Factor Gene Expression in Pig Uterus*

1990 • 128 citations

Characterization of the receptor for epidermal growth factor-urogastrone in human placenta membranes.

1980 • 126 citations

Regulation of polypeptide growth factor synthesis and growth factor-related gene expression in the rat and mouse uterus before and after implantation

1990 • 126 citations

Identification and Characterization of a Rat Decidual Insulin-Like Growth Factor-Binding Protein Complementary DNA

1990 • 124 citations

Effects of products of activated leukocytes (lymphokines and monokines) on the growth of malignant trophoblast cells in vitro

1988 • 123 citations

Expression of insulin-like growth factor-I and -II genes in human smooth muscle tumours.

1988 • 121 citations

Expression of rat transforming growth factor alpha mRNA during development occurs predominantly in the maternal decidua.

1987 • 121 citations

Detection of IL-1 alpha and IL-1 beta gene expression by in situ hybridization. Tissue localization of IL-1 mRNA in the normal C57BL/6 mouse.

1988 • 120 citations

A transforming growth factor beta 2 (TGF-beta 2)-like immunosuppressive factor in amniotic fluid and localization of TGF-beta 2 mRNA in the pregnant uterus.

1990 • 120 citations

Binding Sites for Epidermal Growth Factor in Human Uterine Tissues and Leiomyomas

1984 • 117 citations

Transcription of c-onc genes c-rasKi and c-fms during mouse development.

1983 • 117 citations

Polypeptide growth factors in uterine tissues and secretions

1989 • 117 citations

Demonstration of tumor necrosis factor in human amniotic fluids and supernatants of placental and decidual tissues.

1988 • 117 citations

Identification by Hybridization Histochemistry of Human Endometrial Cells Expressing mRNAs Encoding a Uterine β-Lactoglobulin Homologue and Insulin-Like Growth Factor-Binding Protein-1

1990 • 112 citations

Placental Mononuclear Phagocytes as a Source of Interleukin-1

1982 • 99 citations

The interleukin 2 gene is expressed in the syncytiotrophoblast of the human placenta.

1989 • 98 citations

Presence of epidermal growth factor receptors and influence of epidermal growth factor on proliferation and aging in cultured smooth muscle cells

1979 • 94 citations

Receptors for Epidermal Growth Factor in the Rat Uterus*

1985 • 92 citations

Differential transcription of exon 1 of the human c-fms gene in placental trophoblasts and monocytes.

1989 • 91 citations

Peptide Growth Factors and Proto-oncogenes in Mammalian Conceptus Development1

1991 • 88 citations

Fibroblast growth factor as an intraovarian hormone: differential regulation of steroidogenesis by an angiogenic factor

1986 • 86 citations

Regulation of uterine epidermal growth factor (EGF) receptors by estrogen in the mature rat and during the estrous cycle

1989 • 86 citations

Sex hormones modulate the synthesis of basic fibroblast growth factor in human endometrial adenocarcinoma cells: Implications for the neovascularization of normal and neoplastic endometrium

1988 • 84 citations

Purification of the receptor for platelet-derived growth factor from porcine uterus.

1987 • 83 citations

Interleukin-1 (IL-1) Regulation of Human Endometrial Function: Presence of IL-1 Receptor Correlates with IL-1-Stimulated Prostaglandin E₂Production*

1990 • 82 citations

Secretion of a progesterone-induced inhibitor of plasminogen activator by the porcine uterus

1980 • 81 citations

Expression of the IGF-ll/mannose-6-phosphate receptor mRNA and protein in the developing rat

1990 • 78 citations

Effect of oestradiol-17β on uterine epidermal growth factor concentration in immature mice

1984 • 78 citations

Expression of Acidic and Basic Fibroblast Growth Factors in Human and Bovine Vascular Smooth Muscle Cells

1990 • 78 citations

Receptors for epidermal growth factor and insulin-like growth factor-I on preimplantation trophoderm of the pig

1990 • 75 citations

Binding of epidermal growth factor and insulin-like growth factor I in human myometrium and leiomyomata.

1989 • 73 citations

Products of lipopolysaccharide-activated macrophages (tumor necrosis factor-alpha, transforming growth factor-beta) but not lipopolysaccharide modify DNA synthesis by rat trophoblast cells exhibiting the 80-kDa lipopolysaccharide-binding protein.

1989 • 72 citations

Insulin-Like Growth Factor-I Expression during Early Conceptus Development in the Pig1

1989 • 72 citations

Purification and properties of a mammary-uterine-pituitary tumor cell growth factor from pregnant sheep uterus.

1984 • 68 citations

Topography of human placental receptors for epidermal growth factor.

1985 • 66 citations

Autoradiographic Localization of Epidermal Growth Factor Receptors to All Major Uterine Cell Types1

1988 • 60 citations

Expression of Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-1 in the Rat Uterus during Decidualization*

1990 • 59 citations

Insulin-Like Growth Factor II is a Potent Inhibitor of the Aromatase Activity of Human Placental Cytotrophoblasts*

1990 • 55 citations

Ontogenesis and characteristics of epidermal growth factor receptors in human placenta

1983 • 51 citations

Hormonal regulation of proliferation in two populations of rabbit endometrial cells in culture

1979 • 47 citations

Increased platelet-derived growth factor A-chain expression in human uterine smooth muscle cells during the physiologic hypertrophy of pregnancy.

1990 • 47 citations

Antiestrogens Antagonize the Stimulatory Effect of Epidermal Growth Factor on the Induction of Progesterone Receptor in Fetal Uterine Cells in Culture*

1989 • 43 citations

A role for the insulin-like growth factors as estromedins in the rat uterus.

1987 • 41 citations

Increased Binding of Epidermal Growth Factor at Preimplantation Sites in Mouse Uteri

1989 • 41 citations

In vitro binding of insulin and epidermal growth factor to human endometrium and endocervix

1985 • 40 citations

IL2-like material is present in human placenta and amnion

1987 • 40 citations

Mechanism of menstrual bleeding

1985 • 39 citations

Contractions of the isolated uterus stimulated by epidermal growth factor

1987 • 39 citations

Identification and purification of truncated insulin-like growth factor I from porcine uterus. Evidence for high biological potency

1989 • 38 citations

Epidermal growth factor binding and receptor distribution in term human placenta

1985 • 38 citations

BLASTOCYST PROTEASE AND IMPLANTATION: EFFECT OF OVARIECTOMY AND PROGESTERONE SUBSTITUTION IN THE RABBIT

1972 • 37 citations

Isolation from Bovine Brain and Structural Characterization of HBNF, a Heparin-Binding Neurotrophic Factor

1991 • 36 citations

Progesterone-associated proteins PP12 and PP14 in the human endometrium

1987 • 34 citations

A Uterine Cell Mitogen Distinct from Epidermal Growth Factor in Porcine Uterine Luminal Fluids: Characterization and Partial Purification1

1988 • 34 citations

Species-Specific High Molecular Weight Forms of Basic Fibroblast Growth Factor

1990 • 33 citations

Purification and characterization of heparin-binding growth factors from porcine uterus

1990 • 33 citations

Placental Production of Immunoregulatory Factors: Trophoblast is a Source of Interleukin-1

1987 • 31 citations

Epidermal growth factor binding in rat uterus during the peri-implantation period

1988 • 31 citations

The effect of substrate and epidermal growth factor on human placental trophoblast cells in culture

1986 • 29 citations

Epidermal growth factor receptors on isolated human placental syncytiotrophoblast plasma membrane

1983 • 27 citations

Evidence of high and low affinity binding sites for basic fibroblast growth factor in mouse placenta

1990 • 26 citations

Properties of a growth factor activity present in crude extracts of rat uterus

1981 • 26 citations

Colony-stimulating factor (csf) in the uterus of the pregnant mouse

1975 • 24 citations

Amino-terminal sequences of a novel heparin-binding protein from human, bovine, rat, and chick brain: High interspecies homology

1990 • 23 citations

Existence of both IL-1 alpha and beta in normal human amniotic fluid: unique high molecular weight form of IL-1 beta.

1988 • 21 citations

Mitogenic activity in ovine uterine fluids: Characterization of a growth factor activity which specifically stimulates myoblast proliferations

1988 • 17 citations

Characterization of the mouse placental epidermal growth factor receptor: Changes in receptor number with day of gestation

1986 • 16 citations

Maternal growth factors as mediators of embryonic and neonatal growth

1989 • 15 citations

A unifying hypothesis for the control of blastocyst growth based on observations of the pig.

1981 • 13 citations

Location of the Angiogenic Activity in the Pregnant Human Uterus

1985 • 13 citations

Stimulation of glucose transport in cultured uterine cells by rat and rabbit uterine extracts

1988 • 10 citations

197. Characterization of Epidermal Growth Factor (EGF) Recepter in Human Endometrium and its Cyclic Changes during the Menstrual Cycle

1985 • 5 citations

Deleted Work

1955 • 0 citations