Pancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and C-peptide to measure insulin secretion

Radioimmunological determination of human C-peptide in serum

1975 • 844 citations

C-Peptide as a Measure of the Secretion and Hepatic Extraction of Insulin: Pitfalls and Limitations

1984 • 451 citations

C-peptide Response to Glucagon: A Test for the Residual β-cell Function in Diabetes Mellitus

1977 • 386 citations

THE PLASMA INSULIN RESPONSE TO GLUCOSE INFUSION IN HEALTHY SUBJECTS AND IN DIABETES MELLITUS

1967 • 376 citations

INSULIN DEFICIENCY IN NON-INSULIN-DEPENDENT DIABETES

1989 • 338 citations

Secretion of Proinsulin C-Peptide by Pancreatic β Cells and its Circulation in Blood

1969 • 294 citations

Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated.

1986 • 291 citations

Age as Independent Determinant of Glucose Tolerance

1991 • 259 citations

Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated.

1986 • 242 citations

Pre-Type I Diabetes: Linear Loss of Beta Cell Response to Intravenous Glucose

1984 • 171 citations

Type I Diabetes Mellitus in Monozygotic Twins: Chronic Progressive Beta Cell Dysfunction

1983 • 169 citations

Decreased hepatic insulin extraction in subjects with mild glucose intolerance

1983 • 153 citations

Circulating C-peptide Immunoreactivity: Studies in Normals and Diabetic Patients

1972 • 150 citations

Decreased Insulin Removal Contributes to Hyperinsulinemia in Obesity

1981 • 150 citations

Predictive value of intravenous glucose tolerance test insulin secretion less than or greater than the first percentile in islet cell antibody positive relatives of Type 1 (insulin-dependent) diabetic patients

1991 • 118 citations

Reproducibility and Comparative Analysis of Repeated Intravenous and Oral Glucose Tolerance Tests

1978 • 101 citations

Nonprogression of Subclinical β-Cell Dysfunction Among First-Degree Relatives of IDDM Patients: 5-Yr Follow-Up of the Seattle Family Study

1990 • 85 citations

Between and within subject variation of the first phase insulin response to intravenous glucose

1988 • 62 citations

Peripheral Insulin Parallels Changes in Insulin Secretion More Closely Than C-Peptide After Bolus Intravenous Glucose Administration*

1988 • 57 citations

Clinical Significance of Circulating Proinsulin and C-Peptide

1977 • 49 citations

FURTHER STUDIES ON HEALTHY SUBJECTS WITH LOW AND HIGH INSULIN RESPONSE TO GLUCOSE INFUSION

1967 • 49 citations

The first phase insulin response to intravenous glucose is highly reproducible

1990 • 35 citations

Plasma and urinary C-peptide in the classification of adult diabetics

1986 • 31 citations

Low acute insulin response to intravenous glucose. A sensitive but non-specific marker of early stages of Type 1 (insulin-dependent) diabetes

1988 • 29 citations

Reproducibility of the Glucagon Test

1987 • 20 citations

The plasma C-peptide and insulin responses to stimulation with intravenous glucagon and a mixed meal in well-controlled Type 2 (non-insulin-dependent) diabetes mellitus: dependency on acutely established hyperglycaemia

1989 • 15 citations