Tissue binding of 2-acetylaminofluorene in BALB/c and C57B1/6 mice during chronic oral administration

Promoting effect of saccharin and DL-tryptophan in urinary bladder carcinogenesis.

1979 • 272 citations

On the mechanism of action of carcinogenic aromatic amines

1969 • 138 citations

Effects of dose and time in a long-term, low-dose carcinogenic study.

1980 • 135 citations

Persistent binding of 2-acetylaminofluorene to rat liver DNA in vivo and consideration of the mechanism of binding of N-hydroxy-2-acetylaminofluorene to rat liver nucleic acids.

1969 • 100 citations

The importance of synergy between weak carcinogens in the induction of bladder cancer in experimental animals and humans.

1977 • 95 citations

Biochemistry of carcinogenesis.

1968 • 93 citations

Mechanisms of carcinogenesis: dose response.

1978 • 91 citations

Dose and time responses models for the incidence of bladder and liver neoplasms in mice fed 2-acetylaminofluorene continuously.

1980 • 59 citations

Environmental factors in the origin of cancer and estimation of the possible hazard to man

1975 • 56 citations

The ED01 study: introduction, objectives, and experimental design.

1980 • 51 citations

Difference in binding of 2-acetylaminofluorene to rat liver deoxyribonucleic acid and ribosomal ribonucleic acid in vivo

1968 • 48 citations

Interaction of aromatic amines with rat-liver proteins in vivo

1969 • 40 citations

On the significance and mechanism of the binding of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene to rat-liver ribonucleic acid in vivo.

1967 • 31 citations

Nonlinear dose-response relationship for the binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.

1978 • 30 citations

Metabolism of the carcinogen N-2-Fluorenylacetamide in germ-free and conventional rats

1970 • 29 citations

Estimation of distributions of time to appearance of tumor and time to death from tumor after appearance in mice fed 2-acetylaminofluorene.

1980 • 27 citations

Sex differences in cell proliferation and N-hydroxy-2-acetylaminofluorene sulfotransferase levels in rat liver during 2-acetylaminofluorene administration.

1972 • 26 citations

Chemical carcinogens in the environment and in the human diet: Can a threshold be established?

1974 • 24 citations

Interaction of Aromatic Amines with Rat Liver Proteins in Vivo

1968 • 22 citations

Biochemistry of Carcinogenesis

1967 • 20 citations

Chronic dose‐response studies in mice fed 2‐aaf

1975 • 16 citations

Ultimate electrophilic carcinogens and cellular nucleophilic reactants

1974 • 15 citations

Thresholds in Cancer Induction

1971 • 12 citations

Increased selectivity of interaction between fluorenylamine carcinogens and liver proteins during hepatocarcinogenesis.

1969 • 10 citations

Risk caused by low levels of pollution.

1978 • 7 citations

Preferential binding of 2-acetylaminofluorene to rat liver rRNA during early stages of hepatocarcinogenesis

1972 • 7 citations

Comments on extrapolation of cancer response from high dose to low dose.

1978 • 3 citations