Lipopolysaccharide Activates Nuclear Factor-KappaB through Toll-Like Receptors and Related Molecules in Cultured Biliary Epithelial Cells

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

2001 • 5,526 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Inflammatory Bowel Disease

2002 • 3,038 citations

Bacterial lipopolysaccharides : extraction with phenol-water and further applications of the procedure

1965 • 2,566 citations

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

1999 • 2,188 citations

An Immunohistochemical Study

1989 • 1,928 citations

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

1999 • 1,905 citations

Differential Alteration in Intestinal Epithelial Cell Expression of Toll-Like Receptor 3 (TLR3) and TLR4 in Inflammatory Bowel Disease

2000 • 1,246 citations

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1998 • 1,218 citations

Toll signaling pathways in the innate immune response

2000 • 637 citations

Bacterial Lipopolysaccharide Activates NF-κB through Toll-like Receptor 4 (TLR-4) in Cultured Human Dermal Endothelial Cells

2000 • 556 citations

Toll-like receptors as adjuvant receptors

2002 • 499 citations

Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation

2002 • 481 citations

Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages

2000 • 473 citations

Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

2001 • 388 citations

Development of a sensitive multi-well colorimetric assay for active NFkappaB

2001 • 364 citations

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

2000 • 332 citations

Cutting Edge: Lipopolysaccharide Induces Physical Proximity Between CD14 and Toll-Like Receptor 4 (TLR4) Prior to Nuclear Translocation of NF-κB

2000 • 322 citations

Microstructure and development of the normal and pathologic biliary tract in humans, including blood supply

1997 • 277 citations

Bacterial Invasion Augments Epithelial Cytokine Responses to Escherichia coli Through a Lipopolysaccharide-Dependent Mechanism

2001 • 250 citations

Signaling Events Induced by Lipopolysaccharide-Activated Toll-Like Receptor 2

1999 • 240 citations

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide

2002 • 181 citations

Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: Interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro

1994 • 156 citations

A new human cholangiocellular carcinoma cell line (HuCC-T1) producing carbohydrate antigen 19/9 in serum-free medium

1989 • 140 citations

Abnormal accumulation of endotoxin in biliary epithelial cells in primary biliary cirrhosis and primary sclerosing cholangitis

1998 • 140 citations

Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture study.

1998 • 130 citations

Lipopolysaccharide induces cholangiocyte proliferation via an interleukin-6-mediated activation of p44/p42 mitogen-activated protein kinase

1999 • 119 citations

Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type i ductular reaction in mice: Interactions between the periductal inflammatory and stromal cells and the biliary epithelium

1998 • 102 citations

Lipopolysaccharide Induces Overexpression of MUC2 and MUC5AC in Cultured Biliary Epithelial Cells

2002 • 96 citations

Relationship between interleukin‐6 and proliferation and differentiation in cholangiocarcinoma

1998 • 90 citations

Amplification and sequence analysis of partial bacterial 16S ribosomal RNA gene in gallbladder bile from patients with primary biliary cirrhosis

2000 • 89 citations

Bacterial Peptidoglycan-Inducedtnf-αTranscription Is Mediated Through the Transcription Factors Egr-1, Elk-1, and NF-κB

2001 • 74 citations

Scavenger cells with Gram-positive bacterial lipoteichoic acid infiltrate around the damaged interlobular bile ducts of primary biliary cirrhosis

2001 • 60 citations

Isolation, culture and characterization of biliary epithelial cells from different anatomical levels of the intrahepatic and extrahepatic biliary tree from a mouse

1998 • 53 citations

Lactoferrin and lysozyme in the intrahepatic bile duct of normal livers and hepatolithiasis

1992 • 44 citations

Secretory component and immunoglobulins in the intrahepatic biliary tree and peribiliary gland in normal livers and hepatolithiasis

1989 • 43 citations

Lipopolysaccharides and Beta-Glucuronidase Activity in Choledochal Bile in Relation to Choledocholithiasis

1997 • 38 citations

Re-evaluation of the serotypes of Serratia marcescens and separation into two schemes based on lipopolysaccharide (O) and capsular polysaccharide (K) antigens

1998 • 24 citations

Establishment of the human cholangiocellular carcinoma cell line(CCKS1).

1993 • 23 citations

Generation of monoclonal antibodies to murine bile duct epithelial cells: Identification of annexin V as a new marker of small intrahepatic bile ducts

1999 • 19 citations

Quantification of Lipopolysaccharides in Human Bile with or without Gram-Negative Bacteria

1992 • 9 citations