COPII and selective export from the endoplasmic reticulum

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

1994 • 1,294 citations

Coat Proteins and Vesicle Budding

1996 • 955 citations

Crystal structure of a GA protein βγdimer at 2.1 Å resolution

1996 • 741 citations

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Quality control in the secretory pathway

1995 • 679 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.

1991 • 544 citations

The rate of bulk flow from the endoplasmic reticulum to the cell surface

1987 • 542 citations

Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae

1979 • 518 citations

Visualization of ER-to-Golgi Transport in Living Cells Reveals a Sequential Mode of Action for COPII and COPI

1997 • 510 citations

A Di-Acidic Signal Required for Selective Export from the Endoplasmic Reticulum

1997 • 487 citations

SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER

1993 • 459 citations

A novel GTP-binding protein, Sar1p, is involved in transport from the endoplasmic reticulum to the Golgi apparatus.

1989 • 443 citations

Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack

1989 • 432 citations

COPII–cargo interactions direct protein sorting into ER-derived transport vesicles

1998 • 407 citations

Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum

1994 • 392 citations

Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum

1993 • 375 citations

The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.

1995 • 341 citations

Bimodal Interaction of Coatomer with the p24 Family of Putative Cargo Receptors

1996 • 333 citations

Reconstitution of SEC gene product-dependent intercompartmental protein transport

1988 • 332 citations

Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles.

1991 • 318 citations

Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments.

1994 • 304 citations

COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast

1995 • 278 citations

Density of newly synthesized plasma membrane proteins in intracellular membranes II. Biochemical studies.

1984 • 246 citations

An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding.

1995 • 229 citations

The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins.

1993 • 219 citations

A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding.

1996 • 215 citations

Erv25p, a Component of COPII-coated Vesicles, Forms a Complex with Emp24p That Is Required for Efficient Endoplasmic Reticulum to Golgi Transport

1996 • 210 citations

Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm.

1991 • 196 citations

Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.

1995 • 182 citations

Protein sorting by selective retention in the endoplasmic reticulum and Golgi stack

1987 • 179 citations

Reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex in yeast: the acceptor Golgi compartment is defective in the sec23 mutant.

1988 • 172 citations

Purification and characterization of SAR1p, a small GTP-binding protein required for transport vesicle formation from the endoplasmic reticulum.

1993 • 169 citations

Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations.

1996 • 164 citations

Sorting and retrieval between the endoplasmic reticulum and Golgi apparatus

1995 • 157 citations

Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum.

1997 • 146 citations

Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

1993 • 142 citations

GPI anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles.

1996 • 139 citations

Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles, is required for their fusion competence

1993 • 137 citations

Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain.

1996 • 136 citations

Coats and vesicle budding

1997 • 127 citations

Sec23p and a novel 105-kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the endoplasmic reticulum.

1992 • 126 citations

Fission yeast and a plant have functional homologues of the Sar1 and Sec12 proteins involved in ER to Golgi traffic in budding yeast.

1992 • 124 citations

COPII coat subunit interactions: Sec24p and Sec23p bind to adjacent regions of Sec16p.

1996 • 122 citations

A soluble secretory protein is first concentrated in the endoplasmic reticulum before transfer to the Golgi apparatus.

1993 • 121 citations

Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.

1996 • 120 citations

Characteristics of endoplasmic reticulum-derived transport vesicles.

1994 • 117 citations

Cloning and functional characterization of mammalian homologues of the COPII component Sec23.

1996 • 117 citations

Genes that allow yeast cells to grow in the absence of the HDEL receptor.

1992 • 112 citations

Tmp21 and p24A, Two Type I Proteins Enriched in Pancreatic Microsomal Membranes, Are Members of a Protein Family Involved in Vesicular Trafficking

1996 • 110 citations

Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum.

1995 • 105 citations

SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation.

1995 • 86 citations

Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles

1997 • 81 citations

Uncoupled Packaging of Targeting and Cargo Molecules during Transport Vesicle Budding from the Endoplasmic Reticulum

1995 • 40 citations

Translocon-associated protein TRAP δ and a novel TRAP-like protein are coordinately expressed with pro-opiomelanocortin in Xenopus intermediate pituitary

1995 • 34 citations