The 11q13 amplicon of a mammary carcinoma cell line

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1983 • 1,407 citations

Breast Tumor Cell Lines From Pleural Effusions2

1974 • 973 citations

Recent progress in understanding mechanisms of mammalian DNA amplification

1989 • 469 citations

Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11 ; 14) chromosome translocation

1985 • 446 citations

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.

1986 • 413 citations

Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.

1984 • 400 citations

Metaphase Chromosome Anomaly: Association with Drug Resistance and Cell-Specific Products

1976 • 396 citations

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

1984 • 356 citations

Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.

1989 • 294 citations

Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa.

1986 • 277 citations

The importance of circular DNA in mammalian gene amplification.

1989 • 234 citations

Amplification of cellular oncogenes: A predictor of clinical outcome in human cancer

1990 • 203 citations

Molecular biology and genetics of human neuroblastoma

1989 • 184 citations

Characterization and Chromosome Assignment of the Human Homolog of int-2, a Potential Proto-Oncogene

1986 • 178 citations

Amplification of the int-2 gene in primary human breast tumors.

1988 • 172 citations

High incidence of coamplification of hst-1 and int-2 genes in human esophageal carcinomas.

1989 • 162 citations

The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.

1989 • 160 citations

Proto-oncogene amplification and human breast tumor phenotype

1990 • 154 citations

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line

1983 • 152 citations

Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene.

1986 • 149 citations

ISCN 1985 : an international system for human cytogenetic nomenclature (1985) : report of the Standing Committee on Human Cytogenetic Nomenclature

1985 • 138 citations

Amplification of FGF-related genes in human tumors: possible involvement of HST in breast carcinomas.

1989 • 134 citations

Amplification of human int-2 in breast cancers and squamous carcinomas.

1988 • 125 citations

Isolation of a rearranged human transforming gene following transfection of Kaposi sarcoma DNA.

1987 • 125 citations

The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci.

1989 • 114 citations

Chromosomal localization of the hst oncogene and its co-amplification with the int.2 oncogene in a human melanoma.

1988 • 107 citations

Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.

1989 • 100 citations

Heterogeneity of lung cancer cells with respect to the amplification and rearrangement of myc family oncogenes

1989 • 82 citations

BCL-1 participates in the 11q13 amplification found in breast cancer.

1990 • 78 citations

Cytogenetic and molecular biologic alterations in human breast cancer: A review

1985 • 75 citations

Localization of human ERBA2 to the 3p22----3p24.1 region of chromosome 3 and variable deletion in small cell lung cancer.

1988 • 70 citations

Expression of int-2 mRNA in human tumors amplified at the int-2 locus.

1989 • 62 citations

The human interleukin-1 alpha gene is located on the long arm of chromosome 2 at band q13

1989 • 56 citations

Characterization of N-myc amplification units in human neuroblastoma cells.

1988 • 51 citations

The FGF-related oncogenes hst and int.2, and the bcl.1 locus are contained within one megabase in band q13 of chromosome 11, while the fgf.5 oncogene maps to 4q21.

1988 • 49 citations

Differential expression of two homologous and clustered oncogenes, Hst1 and Int-2, during differentiation of F9 cells

1988 • 48 citations

Amplification and rearrangement of DNA sequences from the chromosomal region 2p24 in human neuroblastomas.

1986 • 48 citations

Biology of the fibroblast growth factor gene family.

1990 • 33 citations

Large scale physical mapping in the q27 region of the human X chromosome: the coagulation factor IX gene and the mcf.2 transforming sequence are separated by at most 270 kilobase pairs and are surrounded by several ‘HTF islands’.

1987 • 31 citations

Structure of amplified DNA, analyzed by pulsed field gradient gel electrophoresis

1987 • 26 citations

A human sequence homologous to v-sea maps to chromosome 11, band q13.

1988 • 22 citations

High-resolution in situ hybridization technique using biotinylated NMYC oncogene probe reveals periodic structure of HSRs in human neuroblastoma

1987 • 21 citations

Near-diploid tumor cell lines for cancer research.

1989 • 6 citations