A laminin-pepsin fragment with cell attachment and neurite outgrowth activity at distinct sites

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

Laminin–a glycoprotein from basement membranes.

1979 • 2,372 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose

1984 • 1,697 citations

Laminin and Other Basement Membrane Components

1987 • 900 citations

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding

1987 • 677 citations

Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix

1981 • 666 citations

The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.

1984 • 634 citations

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction

1989 • 566 citations

Construction of a new family of high efficiency bacterial expression vectors: identification of cDNA clones coding for human liver proteins.

1984 • 538 citations

Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.

1988 • 486 citations

Laminin-nidogen complex. Extraction with chelating agents and structural characterization

1987 • 453 citations

A pentapeptide from the laminin B1 chain mediates cell adhesion and binds to 67000 laminin receptor

1987 • 431 citations

Isolation of a tumor cell laminin receptor

1983 • 426 citations

Laminin receptor on human breast carcinoma cells.

1983 • 419 citations

Appearance and distribution of collagens and laminin in the early mouse embryo

1980 • 395 citations

Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues

1975 • 385 citations

Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats.

1987 • 381 citations

Isolation of a laminin-binding protein from muscle cell membranes

1983 • 354 citations

Laminin is associated with the "neurite outgrowth-promoting factors" found in conditioned media.

1985 • 346 citations

Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion.

1985 • 322 citations

Mapping of domains in human laminin using monoclonal antibodies: localization of the neurite-promoting site.

1986 • 318 citations

Protease Resistance and Conformation of Laminin

1982 • 313 citations

The laminin B2 chain has a multidomain structure homologous to the B1 chain.

1987 • 307 citations

An antibody to a receptor for fibronectin and laminin perturbs cranial neural crest development in vivo

1986 • 304 citations

Increased rate of peripheral nerve regeneration using bioresorbable nerve guides and a laminin-containing gel

1985 • 303 citations

Neural crest cell migratory pathways in the trunk of the chick embryo

1987 • 284 citations

Expression of nidogen and laminin in basement membranes during mouse embryogenesis and in teratocarcinoma cells

1985 • 272 citations

The role of laminin and the laminin/fibronectin receptor complex in the outgrowth of retinal ganglion cell axons

1987 • 267 citations

Subunits of laminin are differentially synthesized in mouse eggs and early embryos

1983 • 263 citations

Retinal ganglion cells lose response to laminin with maturation

1986 • 253 citations

Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT).

1987 • 249 citations

The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.

1987 • 243 citations

Neurite-promoting factors and extracellular matrix components accumulating in vivo within nerve regeneration chambers

1984 • 223 citations

Use of extracellular matrix components for cell culture

1987 • 217 citations

Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth.

1987 • 216 citations

Distribution of laminin in the developing peripheral nervous system of the chick

1986 • 209 citations

Attachment, spreading and locomotion of avian neural crest cells are mediated by multiple adhesion sites on fibronectin molecules.

1988 • 206 citations

Evidence for coiled-coil alpha-helical regions in the long arm of laminin.

1985 • 195 citations

Two distinct cell-binding domains in laminin can independently promote nonneuronal cell adhesion and spreading [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]

1987 • 195 citations

[49] Reaction of proteins with citraconic anhydride

1972 • 177 citations

Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen.

1988 • 167 citations

Genes for basement membrane proteins are coordinately expressed in differentiating F9 cells but not in normal adult murine tissues

1987 • 159 citations

Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies.

1988 • 155 citations

Isolation and characterization of rat schwannoma neurite-promoting factor: evidence that the factor contains laminin

1985 • 152 citations

Immunoreactivity for laminin in the developing ventral longitudinal pathway of the brain

1988 • 148 citations

A novel synthetic peptide from the B1 chain of laminin with heparin-binding and cell adhesion-promoting activities.

1988 • 147 citations

A monoclonal antibody against a laminin-heparan sulfate proteoglycan complex perturbs cranial neural crest migration in vivo.

1988 • 145 citations

Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment.

1988 • 135 citations

Neural crest migration in 3D extracellular matrix utilizes laminin, fibronectin, or collagen

1988 • 129 citations

Identification of a second active site in laminin for promotion of cell adhesion and migration and inhibition of in vivo melanoma lung colonization

1989 • 127 citations

A monoclonal antibody that blocks the activity of a neurite regeneration-promoting factor: studies on the binding site and its localization in vivo.

1986 • 110 citations

Localization of three distinct heparin-binding domains of laminin by monoclonal antibodies.

1988 • 104 citations

[46] Acylation with dicarboxylic acid anhydrides

1972 • 94 citations

Distribution of laminin and fibronectin along peripheral trigeminal axon pathways in the developing chick

1987 • 83 citations

Selective interaction of peripheral and central nervous system cells with two distinct cell-binding domains of fibronectin.

1987 • 82 citations

The neurite-promoting domain of human laminin promotes attachment and induces characteristic morphology in non-neuronal cells

1988 • 65 citations

An in Vitro Neurite-Promoting Antigen Functions in Axonal Regeneration in Vivo

1987 • 64 citations

Characterization of Pepsin Fragments of Laminin in a Tumor Basement Membrane. Evidence for the Existence of Related Proteins

1980 • 58 citations

Behavior of neural crest cells on embryonic basal laminae

1987 • 56 citations

Laminin Neural Activity and Binding Proteins

1989 • 53 citations

Functional activity of rat brainstem neurons regenerating axons along peripheral nerve grafts

1985 • 49 citations

Nerve growth factors and molecules of the extracellular matrix in neuronal development

1985 • 45 citations

Alternative model for the internal structure of laminin

1985 • 41 citations

A second cell-binding domain on fibronectin (RGDS-independent) for neurite extension of human neuroblastoma cells

1987 • 41 citations

Cell adhesion and neurite extension in response to two proteolytic fragments of laminin

1988 • 14 citations