Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy

Tumor Biologic Factors and Breast Cancer Prognosis Among White, Hispanic, and Black Women in the United States

1994 • 426 citations

NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.

1992 • 313 citations

DT-diaphorase and cancer chemotherapy

1992 • 284 citations

Reductase Enzyme Expression Across the National Cancer Institute Tumor Cell Line Panel: Correlation With Sensitivity to Mitomycin C and EO9

1996 • 232 citations

Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.

1990 • 222 citations

DT-diaphorase in activation and detoxification of quinones

1993 • 188 citations

Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase.

1994 • 127 citations

The Role of NAD(P)H: Quinone Reductase (EC 1.6.99.2, DT-Diaphorase) in the Reductive Bioactivation of the Novel Indoloquinone Antitumor Agent E09

1991 • 122 citations

Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies.

1994 • 106 citations

Cancer in Hispanics: issues of concern.

1995 • 25 citations

Response to treatment of breast cancer

1991 • 5 citations