Quantitative Measurement of Human T-Cell Receptor Vβ Subfamilies by Reverse Transcription-Polymerase Chain Reaction Using Synthetic Internal mRNA Standards

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.

1990 • 1,484 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

1989 • 1,000 citations

Transcription of the dystrophin gene in human muscle and non-muscle tissues

1988 • 733 citations

Vβ-Specific Stimulation of Human T Cells by Staphylococcal Toxins

1989 • 711 citations

Absolute mRNA quantification using the polymerase chain reaction (PCR). A novel approach by aPCR aidedtranscipttitration assay (PATTY)

1989 • 659 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

Use of the polymerase chain reaction in the quantitation of MDR-1 gene expression

1990 • 427 citations

Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients

1990 • 395 citations

Shared Human T Cell Receptor V _β Usage to Immunodominant Regions of Myelin Basic Protein

1990 • 386 citations

Novel method for studying mRNA phenotypes in single or small numbers of cells

1989 • 382 citations

Selective Depletion in HIV Infection of T Cells that Bear Specific T Cell Receptor V _β Sequences

1991 • 322 citations

Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody.

1991 • 250 citations

Evidence of Limited Variability of Antigen Receptors on Intrathyroidal T Cells in Autoimmune Thyroid Disease

1991 • 207 citations

Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction.

1991 • 206 citations

Quantitative estimation of minor mRNAs by cDNA‐polymerase chain reaction

1990 • 196 citations

Restricted expression of T cell receptor V_β but not V_α genes in rheumatoid arthritis

1991 • 189 citations

Bias toward use of a specific T cell receptor beta-chain variable region in a subgroup of individuals with sarcoidosis.

1988 • 156 citations

Gut mucosal lymphocytes in inflammatory bowel disease

1979 • 132 citations

T cell antigen receptor V gene usage. Increases in V beta 8+ T cells in Crohn's disease.

1990 • 113 citations

T cell receptor gene rearrangements of T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis (PBC): Oligoclonality of PBC‐derived T cell clones

1990 • 95 citations

Evidence for selective accumulation of intrathyroidal T lymphocytes in human autoimmune thyroid disease based on T cell receptor V gene usage.

1992 • 80 citations

Determining transcript number using the polymerase chain reaction:Pgk-2,mP2, andPGK-2transgene mRNA levels during spermatogenesis

1991 • 77 citations

Expression of the human T cell receptor Vβ repertoire

1991 • 45 citations

Configuration and expression of the T cell receptor beta chain gene in human T-lymphotrophic virus I-infected cells.

1986 • 21 citations