An aminoacyl tRNA synthetase binds to a specific DNA sequence and regulates its gene transcription

A new method for sequencing DNA.

1977 • 7,941 citations

REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTION

1979 • 2,730 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Procedures in nucleic acid research

1966 • 987 citations

Aminoacyl-tRNA Synthetases: General Features and Recognition of Transfer RNAs

1979 • 636 citations

The Nucleotide Sequence of the lac Operator

1973 • 480 citations

Patterns of protein synthesis in E. coli: a catalog of the amount of 140 individual proteins at different growth rates

1978 • 398 citations

Levels of major proteins of Escherichia coli during growth at different temperatures

1979 • 372 citations

Interactions between DNA-bound repressors govern regulation by the λ phage repressor

1979 • 329 citations

Polynucleotide kinase exchange reaction: quantitave assay for restriction endonuclease-generated 5'-phosphoroyl termini in DNA.

1977 • 289 citations

The interaction of RNA polymerase and lac repressor with the lac control region

1979 • 283 citations

Transfer RNA: Biological Aspects

1981 • 274 citations

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency.

1975 • 240 citations

Chemical measurement of steady-state levels of ten aminoacyl-transfer ribonucleic acid synthetases in Escherichia coli

1977 • 235 citations

In vitro expression of Escherichia coli ribosomal protein genes: autogenous inhibition of translation.

1980 • 178 citations

The Catalytic Properties of Tyrosyl Ribonucleic Acid Synthetases from Escherichia coli and Bacillus subtilis^*

1966 • 178 citations

Amino Acid Transport Systems in Escherichia coli K12

1968 • 176 citations

Nucleotide sequence of the leader region of the phenylalanine operon of Escherichia coli

1978 • 156 citations

DNA sequence from the histidine operon control region: seven histidine codons in a row.

1978 • 156 citations

Protein L4 of the E. coli ribosome regulates an eleven gene r protein operon

1980 • 149 citations

FUNCTION AND REGULATION OF AMINOACYL-tRNA SYNTHETASES IN PROKARYOTIC AND EUKARYOTIC CELLS

1975 • 142 citations

Multivalent translational control of transcription termination at attenuator of ilvGEDA operon of Escherichia coli K-12.

1980 • 130 citations

Studies on Methionyl Transfer RNA Synthetase

1968 • 125 citations

E. coli ribosomal protein L4 is a feedback regulatory protein

1980 • 119 citations

Regulation of the threonine operon: tandem threonine and isoleucine codons in the control region and translational control of transcription termination.

1979 • 115 citations

Studies on valyl-tRNA synthetase and tRNAVal from Escherichia coli,

1969 • 106 citations

Feedback regulation of ribosomal protein gene expression in Escherichia coli.

1980 • 105 citations

Regulation of the in vivo synthesis of the polypeptide chain elongation factors in Escherichia coli

1970 • 101 citations

Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli.

1980 • 99 citations

leu operon of Salmonella typhimurium is controlled by an attenuation mechanism.

1979 • 97 citations

Nucleotide sequence of the attenuator region of the histidine operon of Escherichia coli K-12.

1978 • 97 citations

Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits.

1981 • 92 citations

TRANSFER RNA INVOLVEMENT IN THE REGULATION OF ENZYME SYNTHESIS

1975 • 90 citations

Rate law and mechanism of the adenosine triphosphate-pyrophosphate isotope exchange reaction of amino acyl transfer ribonucleic acid synthetases

1970 • 89 citations

Tryptophanyl Transfer Ribonucleic Acid Synthetase of Escherichia coli

1971 • 87 citations

Dual-control of the tryptophan operon is mediated by both tryptophanyl-tRNA synthetase and the repressor

1976 • 76 citations

Nucleotide sequence of region preceding trp mRNA initiation site and its role in promoter and operator function.

1976 • 74 citations

Relationships Among Deoxyribonucleic Acid, Ribonucleic Acid, and Specific Transfer Ribonucleic Acids in Escherichia coli 15T ⁻ at Various Growth Rates

1973 • 73 citations

Glycyl transfer ribonucleic acid synthetase from Escherichia coli. Purification, properties, and substrate binding

1974 • 72 citations

The lac Repressor Protein: Molecular Shape, Subunit Structure, and Proposed Model for Operator Interaction Based on Structural Studies of Microcrystals

1974 • 69 citations

Purification and Properties of Seryl Transfer Ribonucleic Acid Synthetase from Escherichia coli

1970 • 67 citations

Post-transcriptional regulatory mutants in a ribosomal protein-RNA polymerase operon of E. coli

1980 • 57 citations

Regulation of the Biosynthesis of Aminoacid:tRNA Ligases and of †RNA

1978 • 53 citations

Cloning, partial sequencing, and in vitro transcription of the gene for alanine tRNA synthetase.

1981 • 39 citations

Leucyl‐tRNA Synthetase

1970 • 37 citations

The Biochemical Characterization of Two Mutant Arginyl Transfer Ribonucleic Acid Synthetases from Escherichia coli K-12

1969 • 33 citations

Isolation and Characterization of a Regulatory Mutant of an Aminoacyl-Transfer Ribonucleic Acid Synthetase in Escherichia coli K-12

1973 • 32 citations

Purification and characterization of histidyl transfer ribonucleic acid synthetase of Escherichia coli

1974 • 30 citations

Role of Histidine Transfer Ribonucleic Acid in Regulation of Synthesis of Histidyl-Transfer Ribonucleic Acid Synthetase of Salmonella typhimurium

1972 • 28 citations

Regulation of biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli

1977 • 26 citations

Regulation of Histidyl-Transfer Ribonucleic Acid Synthetase Formation in a Histidyl-Transfer Ribonucleic Acid Synthetase Mutant of Salmonella typhimurium

1972 • 22 citations

Regulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. V. Mutants with increased levels of valyl-transfer ribonucleic acid synthetase

1979 • 17 citations

Two modes of metabolic regulation of lysyl-transfer ribonucleic acid synthetase in Escherichia coli K-12

1977 • 15 citations

Characterization of a mutant of E.coli with elevated levels of seryl-tRNA synthetase

1972 • 12 citations

DNA‐dependent in vitro synthesis of Escherichia coli ribosomal protein S20 and isoleucyl‐tRNA synthetase effect of guanosine‐5′‐diphosphate‐3′‐diphosphate

1977 • 9 citations