Depolarization Induces Intersubunit Cross-linking in a S4 Cysteine Mutant of the Shaker Potassium Channel

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

1998 • 6,595 citations

Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution

2001 • 2,033 citations

Ion Channels/Excitable Membranes

2006 • 2,013 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin

1996 • 1,159 citations

The Voltage Sensor in Voltage-Dependent Ion Channels

2000 • 854 citations

Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

2001 • 586 citations

Transmembrane Movement of the Shaker K+ Channel S4

1996 • 496 citations

The moving parts of voltage-gated ion channels

1998 • 473 citations

Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy

1999 • 466 citations

Dynamic Rearrangement of the Outer Mouth of a K+ Channel during Gating

1996 • 451 citations

Voltage gating of ion channels

1994 • 405 citations

Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels

1998 • 401 citations

Evidence for voltage-dependent S4 movement in sodium channels

1995 • 396 citations

Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel

1999 • 276 citations

[10] Reductive cleavage of cystine disulfides with tributylphosphine

1977 • 249 citations

Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits

1997 • 207 citations

Correlation between Charge Movement and Ionic Current during Slow Inactivation in Shaker K+ Channels

1997 • 186 citations

Protein Rearrangements Underlying Slow Inactivation of the Shaker K+ Channel

1998 • 185 citations

Three Transmembrane Conformations and Sequence-Dependent Displacement of the S4 Domain in Shaker K + Channel Gating

1998 • 172 citations

α-Helical Structural Elements within the Voltage-Sensing Domains of a K+ Channel

1999 • 163 citations

Constraining Ligand-Binding Site Stoichiometry Suggests that a Cyclic Nucleotide–Gated Channel Is Composed of Two Functional Dimers

1998 • 136 citations

Lock On/Off Disulfides Identify the Transmembrane Signaling Helix of the Aspartate Receptor

1995 • 133 citations

Helical Structure and Packing Orientation of the S2 Segment in the Shaker K+ Channel

1999 • 132 citations

Voltage-Dependent Structural Interactions in the Shaker K+ Channel

2000 • 131 citations

Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel

1996 • 129 citations

A Localized Interaction Surface for Voltage-Sensing Domains on the Pore Domain of a K+ Channel

2000 • 117 citations

A Conserved Glutamate Is Important for Slow Inactivation in K+ Channels

2000 • 110 citations

Structural Models of the Transmembrane Region of Voltage-Gated and Other K+Channels in Open, Closed, and Inactivated Conformations

1998 • 102 citations

Molecular Coupling of S4 to a K+ Channel's Slow Inactivation Gate

2000 • 98 citations

Tethered blockers as molecular 'tape measures' for a voltage-gated K+ channel.

2000 • 98 citations

Reconstructing Voltage Sensor–Pore Interaction from a Fluorescence Scan of a Voltage-Gated K+ Channel

2000 • 94 citations

Evidence for Dimerization of Dimers in K+ Channel Assembly

1999 • 80 citations

S4 Charges Move Close to Residues in the Pore Domain during Activation in a K Channel

2001 • 76 citations

Stoichiometry and Arrangement of Subunits in Rod Cyclic Nucleotide–Gated Channels

1999 • 61 citations

Localization of the Extracellular End of the Voltage Sensor S4 in a Potassium Channel

2001 • 48 citations

Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore

1997 • 45 citations

Cysteines in the Shaker K+ channel are not essential for channel activity or zinc modulation

1994 • 37 citations

S4 Charges Move Close to Residues in the Pore Domain during Activation in a K Channel

2001 • 36 citations

Effect of cysteine substitutions on the topology of the S4 segment of the Shaker potassium channel: implications for molecular models of gating

1999 • 33 citations

Dimers among friends: ion channel regulation by dimerization of tail domains

2001 • 7 citations