CGEMA and VGAP: a Colour Graphics Editor for Multiple Alignment using a Variable GAP penalty. Application to the muscarinic acetylcholine receptor

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

Atlas of protein sequence and structure

1965 • 4,462 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450.

1985 • 815 citations

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

1988 • 792 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.

1982 • 737 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

Primary Structure and Biochemical Properties of an M ₂ Muscarinic Receptor

1987 • 510 citations

The Site of Attachment in Human Rhinovirus 14 for Antiviral Agents That Inhibit Uncoating

1986 • 462 citations

Identification of residues required for ligand binding to the beta-adrenergic receptor.

1987 • 398 citations

Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence

1986 • 344 citations

Ligand binding to the β-adrenergic receptor involves its rhodopsin-like core

1987 • 318 citations

Hemoglobin as a receptor of drugs and peptides: x-ray studies of the stereochemistry of binding

1986 • 290 citations

Molecular cloning and expression of a fifth muscarinic acetylcholine receptor

1989 • 182 citations

Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family.

1987 • 181 citations

Propylbenzilylcholine Mustard Labels an Acidic Residue in Transmembrane Helix 3 of the Muscarinic Receptor

1989 • 146 citations

Isolation, sequence, and functional expression of the mouse M1 muscarinic acetylcholine receptor gene.

1988 • 126 citations

Primary structure of porcine muscarinic acetylcholine receptor III and antagonist binding studies

1988 • 94 citations

Muscarinic cholinergic receptor structure: molecular biological support for subtypes

1987 • 86 citations

Separating receptor subtypes from their shadows

1988 • 53 citations

A novel subtype of muscarinic receptor identified by homology screening

1987 • 49 citations

Sequence of the gene encoding the human M1 muscarinic acetylcholine receptor

1987 • 47 citations

The random character of protein evolution and its effects on the reliability of phylogenetic information deduced from amino acid sequences and compositions

1980 • 20 citations

Carboxyl residue(s) at the ligand-binding site of rat muscarinic receptors

1988 • 4 citations