Modulation of Methyl Group Metabolism by Streptozotocin-induced Diabetes and All-trans-retinoic Acid

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Hyperhomocyst(e)inemia as a Risk Factor for Occlusive Vascular Disease

1992 • 726 citations

Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum

1991 • 702 citations

Methionine metabolism in mammals. Distribution of homocysteine between competing pathways.

1984 • 414 citations

Mammalian methylenetetrahydrofolate reductase Partial purification, properties, and inhibition by S-adenosylmethionine

1971 • 349 citations

Vitamin B₁₂-Folate Interrelationships

1985 • 306 citations

Competing Methyltransferase Systems

1972 • 270 citations

Folate in Health and Disease

1996 • 255 citations

Purification, Kinetic Properties, and cDNA Cloning of Mammalian Betaine-Homocysteine Methyltransferase

1996 • 236 citations

Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat.

1998 • 194 citations

Diet and DNA Methylation Interactions in Cancer Prevention

2003 • 188 citations

Inhibition of glycine n-methyltransferase activity by folate derivatives: Implications for regulation of methyl group metabolism

1985 • 169 citations

Common gene polymorphisms and nutrition: emerging links with pathogenesis of multifactorial chronic diseases (review)

2003 • 160 citations

Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium.

1987 • 159 citations

Glycine N-methyltransferase is a folate binding protein of rat liver cytosol.

1984 • 147 citations

Hormonal Regulation of Cystathionine β-Synthase Expression in Liver

2002 • 141 citations

Natural Sulfur Compounds

1980 • 134 citations

Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver.

1994 • 126 citations

Hepatic one-carbon metabolism in early folate deficiency in rats

1993 • 121 citations

Vitamin A and Its Derivatives Induce Hepatic Glycine N-Methyltransferase and Hypomethylation of DNA in Rats

2002 • 105 citations

Use of isotretinoin (Accutane) in the United States: Rapid increase from 1992 through 2000

2002 • 100 citations

Effect of Dietary Methyl Group Deficiency on One-Carbon Metabolism in Rats

1989 • 74 citations

The Role of Nutrition in Neural Tube Defects

1990 • 71 citations

Hyperglucagonemia in Rats Results in Decreased Plasma Homocysteine and Increased Flux through the Transsulfuration Pathway in Liver

2001 • 60 citations

Glucocorticoid Regulation of HepaticS-Adenosylmethionine Synthetase Gene Expression¹

1997 • 55 citations

Determination of adenosine and s-adenosyl derivatives of sulfur amino acids in rat liver by high-performance liquid chromatography

1985 • 55 citations

Retinoic Acid and Glucocorticoid Treatment Induce Hepatic Glycine N-Methyltransferase and Lower Plasma Homocysteine Concentrations in Rats and Rat Hepatoma Cells

2003 • 49 citations

Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies

2003 • 49 citations

Phosphorylation Modulates the Activity of Glycine N-Methyltransferase, a Folate Binding Protein

1989 • 49 citations

Rat glycine methyltransferase. Complete amino acid sequence deduced from a cDNA clone and characterization of the genomic DNA

1987 • 42 citations

All-trans-Retinoic Acid Rapidly Induces Glycine N-methyltransferase in a Dose-Dependent Manner and Reduces Circulating Methionine and Homocysteine Levels in Rats

2003 • 36 citations

Retinoid Compounds Activate and Induce Hepatic Glycine N-Methyltransferase in Rats

2001 • 35 citations

Activation and induction of glycine N-methyltransferase by retinoids are tissue- and gender-specific

2002 • 32 citations

Demonstration of methionine synthetase in intestinal mucosal cells of the rat

1985 • 23 citations

Methotrexate alters carbon flow through the hepatic folate-dependent one-carbon pool in rats

1996 • 22 citations