Modelling molecular mechanisms of breast cancer and invasion: lessons from the normal gland

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

1997 • 1,444 citations

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

2005 • 1,225 citations

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

1992 • 1,047 citations

The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis

1999 • 916 citations

β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

2002 • 772 citations

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane

1989 • 700 citations

Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes

1977 • 641 citations

Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology

1998 • 625 citations

Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures

2006 • 592 citations

Tissue architecture: the ultimate regulator of breast epithelial function

2003 • 449 citations

β1 Integrin Inhibitory Antibody Induces Apoptosis of Breast Cancer Cells, Inhibits Growth, and Distinguishes Malignant from Normal Phenotype in Three Dimensional Cultures and In vivo

2006 • 314 citations

Taking the Study of Cancer Cell Survival to a New Dimension

2002 • 302 citations

Inability of Rous sarcoma virus to cause sarcomas in the avian embryo

1984 • 202 citations

Gene Expression Signature in Organized and Growth-Arrested Mammary Acini Predicts Good Outcome in Breast Cancer

2006 • 126 citations

Characterization of BCE-1, a Transcriptional Enhancer Regulated by Prolactin and Extracellular Matrix and Modulated by the State of Histone Acetylation

1998 • 102 citations

Disruption of 3D tissue integrity facilitates adenovirus infection by deregulating the coxsackievirus and adenovirus receptor

2003 • 101 citations

The embryonic environment strongly attenuates v-src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia.

1990 • 87 citations