Analysis of tetanus toxin peptide/DR recognition by human T cell receptors reconstituted into a murine T cell hybridoma

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens

1984 • 655 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

1992 • 531 citations

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

1983 • 436 citations

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1991 • 417 citations

Selective expansion of T cells expressing V beta 2 in toxic shock syndrome.

1990 • 359 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.

1991 • 323 citations

Interactions between Immunogenic Peptides and MHC Proteins

1991 • 303 citations

Atomic structure of a human MHC molecule presenting an influenza virus peptide

1992 • 254 citations

Structure of Antibody-Antigen Complexes: Implications for Immune Recognition

1988 • 207 citations

Selection of Amino Acid Sequences in the Beta Chain of the T Cell Antigen Receptor

1988 • 203 citations

Implications of a Fab-like structure for the T-cell receptor

1989 • 193 citations

Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α‐mRNA of BW5147 origin

1989 • 188 citations

The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides.

1990 • 183 citations

Site-directed mutations in the VDJ junctional region of a T cell receptor β chain cause changes in antigenic peptide recognition

1988 • 180 citations

Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition.

1991 • 159 citations

Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition.

1992 • 150 citations

HLA-DR and -DQ epitopes and monoclonal antibody specificity

1989 • 150 citations

H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity.

1992 • 102 citations

An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain

1992 • 100 citations

Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules.

1988 • 98 citations

Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor.

1993 • 89 citations

Transfer of putative complementarity-determining region loops of T cell receptor V domains confers toxin reactivity but not peptide/MHC specificity.

1993 • 89 citations

Truncation analysis of several DR binding epitopes.

1991 • 76 citations

Restricted V-(D)-J junctional regions in the T cell response to lambda-repressor. Identification of residues critical for antigen recognition.

1990 • 76 citations

Involvement of both T cell receptor V_α and V_β variable region domains and α chain junctional region in viral antigen recognition

1991 • 68 citations

Structure-function relationships among highly diverse T cells that recognize a determinant from influenza virus hemagglutinin.

1990 • 61 citations

T cell receptor junctional regions and the MHC molecule affect the recognition of antigenic peptides by T cell clones.

1990 • 52 citations

Amino acid residues in the T cell receptor CDR3 determine the antigenic reactivity patterns of insulin-reactive hybridomas.

1991 • 40 citations

Functional analysis of the antigen binding site on the T cell receptor alpha chain.

1992 • 39 citations

Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor.

1985 • 37 citations

Position 71 in the α helix of the DRβ domain is predicted to influence peptide binding and plays a central role in allorecognition

1993 • 32 citations

Antigen-specific T cells with monogamous or promiscuous restriction patterns are sensitive to different HLA-DR beta chain substitutions.

1991 • 31 citations

The role of polymorphic HLA-DR beta chain residues in presentation of viral antigens to T cells.

1990 • 31 citations

Expression of the Alpha Chain of Human FcεRI in Transfected Rat Basophilic Leukemia Cells: Functional Activation after Sensitization with Human Mite-Specific IgE

1993 • 30 citations

T cell receptor selection by and recognition of two class I major histocompatibility complex-restricted antigenic peptides that differ at a single position.

1993 • 29 citations

Alloreactive T cells can distinguish between the same human class II MHC products on different B cell lines.

1991 • 13 citations