Promoter-independent activation of heterologous virus gene expression by the herpes simplex virus immediate-early protein ICP27

DNA cloning : a practical approach

1985 • 2,302 citations

High efficiency gene transfer into mammalian cells

1984 • 498 citations

Herpes simplex virus type 1 ICP27 is an essential regulatory protein

1985 • 462 citations

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1985 • 345 citations

Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1

1986 • 335 citations

Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

1989 • 329 citations

Activation of human immunodeficiency virus by herpesvirus infection: identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1.

1987 • 234 citations

The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0

1988 • 202 citations

Characterization of the IE110 Gene of Herpes Simplex Virus Type 1

1986 • 192 citations

Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27

1988 • 167 citations

The Products of Herpes Simplex Virus Type 1 (HSV-1) Immediate Early Genes 1, 2 and 3 Can Activate HSV-1 Gene Expression in trans

1986 • 163 citations

Activation of the human immunodeficiency virus by herpes simplex virus type 1

1987 • 156 citations

The regulation of transcription of viral and cellular genes by herpesvirus immediate-early gene products (review).

1987 • 102 citations

Herpes simplex virus immediate-early promoters are responsive to virus and cell trans-acting factors

1987 • 94 citations

Herpes simplex Virus a Protein ICP27 Can Inhibit or Augment Viral Gene Transactivation

1989 • 94 citations

Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities

1989 • 92 citations

Cytomegalovirus activates transcription directed by the long terminal repeat of human immunodeficiency virus type 1

1990 • 83 citations

The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule

1989 • 83 citations

Identification of a region within the human immunodeficiency virus type 1 long terminal repeat that is essential for transactivation by the hepatitis B virus gene X

1989 • 68 citations

Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene

1991 • 61 citations

Delineation of regulatory domains of early (beta) and late (gamma 2) genes by construction of chimeric genes expressed in herpes simplex virus 1 genomes.

1989 • 43 citations

Multiple transcriptional regulatory domains in the human immunodeficiency virus type 1 long terminal repeat are involved in basal and E1A/E1B-induced promoter activity

1989 • 38 citations

The Epstein-Barr virus BRLF1 immediate-early gene product transactivates the human immunodeficiency virus type 1 long terminal repeat by a mechanism which is enhancer independent

1990 • 31 citations

The herpes simplex virus type 1 immediate-early protein icp27 is obligately required for the accumulation of a cellular protein during viral infection

1989 • 14 citations

A recombinant HIV provirus is synergistically activated by the HIV Tat protein and the HSV IE1 protein but not by the HSV IE3 protein

1991 • 13 citations