EGFR Dinucleotide Repeat Polymorphism as a Prognostic Indicator in Non-small Cell Lung Cancer

Classification and Regression Trees.

1984 • 23,117 citations

Classification and Regression Trees.

1986 • 21,574 citations

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

2004 • 11,185 citations

Classification and regression trees

1985 • 11,138 citations

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

2004 • 9,201 citations

Untangling the ErbB signalling network

2001 • 6,623 citations

Cancer Statistics, 2006

2006 • 5,351 citations

Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer

2002 • 2,968 citations

Mutations in the Epidermal Growth Factor Receptor and in KRAS Are Predictive and Prognostic Indicators in Patients With Non–Small-Cell Lung Cancer Treated With Chemotherapy Alone and in Combination With Erlotinib

2005 • 1,467 citations

Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on Prognosis

2003 • 1,445 citations

A Randomized Trial of Postoperative Adjuvant Therapy in Patients with Completely Resected Stage II or IIIa Non–Small-Cell Lung Cancer

2000 • 444 citations

neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group.

1998 • 435 citations

Modulation of Epidermal Growth Factor Receptor Gene Transcription by a Polymorphic Dinucleotide Repeat in Intron 1

1999 • 383 citations

Epidermal growth factor receptor family in lung cancer and premalignancy

2002 • 303 citations

An Epidermal Growth Factor Receptor Intron 1 Polymorphism Mediates Response to Epidermal Growth Factor Receptor Inhibitors

2004 • 243 citations

Evaluation of the epidermal growth factor receptor (EGFR) in colorectal tumours and lymph node metastases

2002 • 219 citations

Lack of Prognostic Significance of p53 and K-ras Mutations in Primary Resected Non–Small-Cell Lung Cancer on E4592: A Laboratory Ancillary Study on an Eastern Cooperative Oncology Group Prospective Randomized Trial of Postoperative Adjuvant Therapy

2001 • 197 citations

Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage.

2003 • 169 citations

Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism.

2003 • 158 citations

Length and loss of heterozygosity of an intron 1 polymorphic sequence of egfr is related to cytogenetic alterations and epithelial growth factor receptor expression.

2000 • 148 citations

The human EGF receptor gene: structure of the 110 kb locus and identification of sequences regulating its transcription.

1987 • 121 citations

Two chromosome 7 dinucleotide repeat polymorphisms at gene loci epidermal growth factor receptor (EGFR) and proα2 (1) collagen (COL1A2)

1992 • 66 citations

Modification of Breast Cancer Risk in Young Women by a Polymorphic Sequence in the egfr Gene

2004 • 62 citations

Modulation of proliferating cell nuclear antigen in the bronchial epithelium of smokers.

2001 • 37 citations

A strong intronic enhancer element of the EGFR gene is preferentially active in high EGFR expressing breast cancer cells

2001 • 37 citations

P-615 Phase II trials of gefitinib (‘Iressa’, ZD1839): rapid and durable objective responses in patients with advanced non-small-cell lung cancer (IDEAL 1 and IDEAl 2)

2003 • 20 citations

Lack of prognostic significance of p53 and K-ras mutations in primary resected non-small cell lung cancer: Results from an ECOG prospective randomized trial of postoperative adjuvant therapy (E3590, INT0015)

2000 • 2 citations