Immunological Effects of BCG as an Adjuvant in Autologous Tumor Vaccines
Data up to Jan 2025
Total Citations Per Year
Abstract
References (41)
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.
1995 • 1,560 citations
THE TREATMENT OF MALIGNAT TUMORS BY REPEATED INOCULATIONS OF ERYSIPELAS
1893 • 946 citations
Encyclopedia of Statistical Sciences.
1989 • 736 citations
A Randomized Trial of Intravesical Doxorubicin and Immunotherapy with Bacille Calmette–Guérin for Transitional-Cell Carcinoma of the Bladder
1991 • 605 citations
Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside.
1994 • 522 citations
Active specific immunotherapy for stage II and stage III human colon cancer: a randomised trial
1999 • 495 citations
Immunological factors which influence response to immunotherapy in malignant melanoma.
1970 • 462 citations
Prolongation of Survival in Metastatic Melanoma After Active Specific Immunotherapy With a New Polyvalent Melanoma Vaccine
1992 • 410 citations
Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes.
1991 • 402 citations
Intravesical bacillus Calmette-Guérin therapy prevents tumor progression and death from superficial bladder cancer: ten-year follow-up of a prospective randomized trial.
1995 • 305 citations
Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients.
1990 • 300 citations
Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a phase III prospectively randomized trial.
1993 • 255 citations
Requirement of a Thymus Dependent Immune Response for Bcg-mediated Antitumor Activity
1987 • 229 citations
Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2.
1991 • 217 citations
Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2.
1997 • 167 citations
Correlation of specific immune responses with survival in melanoma patients with distant metastases receiving polyvalent melanoma cell vaccine.
1998 • 162 citations
Gene-Modified Tumor Vaccine with Therapeutic Potential Shifts Tumor-Specific T Cell Response from a Type 2 to a Type 1 Cytokine Profile
1998 • 154 citations
Induction of IFN-γ-producing CD4+ natural killer T cells byMycobacterium bovis bacillus Calmette Guérin
1999 • 126 citations
Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells
1997 • 125 citations
Type 1 versus type 2 cytokine release by Vbeta T cell subpopulations determines in vivo antitumor reactivity: IL-10 mediates a suppressive role.
1997 • 119 citations
Purification of L-Selectinlow Cells Promotes the Generation of Highly Potent CD4 Antitumor Effector T Lymphocytes
1998 • 110 citations
Sequential production of Th1 and Th2 cytokines in response to live bacillus Calmette-Guérin.
1995 • 102 citations
Generation of therapeutic T lymphocytes from tumor-bearing mice by in vitro sensitization. Culture requirements and characterization of immunologic specificity.
1988 • 99 citations
HLA—DR Expression by High Grade Superficial Bladder Cancer Treated with BCG
1989 • 93 citations
Lymphocytes generated by in vivo priming and in vitro sensitization demonstrate therapeutic efficacy against a murine tumor that lacks apparent immunogenicity.
1989 • 89 citations
Clinical observations on adoptive immunotherapy with vaccine-primed T-lymphocytes secondarily sensitized to tumor in vitro.
1993 • 88 citations
The Role of Tumor Necrosis Factor α in Modulating the Quantity of Peripheral Blood-Derived, Cytokine-Driven Human Dendritic Cells and Its Role in Enhancing the Quality of Dendritic Cell Function in Presenting Soluble Antigens to CD4+ T Cells In Vitro
1998 • 84 citations
Research on BCG vaccination.
1984 • 83 citations
Activation by anti-CD3 of tumor-draining lymph node cells for specific adoptive immunotherapy
1991 • 75 citations
Adoptive immunotherapy of microscopic and advanced visceral metastases with in vitro sensitized lymphoid cells from mice bearing progressive tumors.
1988 • 64 citations
Generation of T-Cells Reactive to the Poorly Immunogenic B16-BL6 Melanoma with Efficacy in the Treatment of Spontaneous Metastases
1993 • 59 citations
Induction of TH1- and TH2-associated cytokine mRNA in mouse bladder following intravesical growth of the murine bladder tumor MB49 and BCG immunotherapy
1994 • 56 citations
Cellular interactions in effector cell generation and tumor regression mediated by anti-CD3/interleukin 2-activated tumor-draining lymph node cells.
1992 • 55 citations
Adjuvant therapy for melanoma
1997 • 54 citations
Tumor-specific granulocyte/macrophage colony-stimulating factor and interferon ? secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells
1995 • 51 citations
Expanded tumor-reactive CD4+ T-cell responses to human cancers induced by secondary anti-CD3/anti-CD28 activation.
1999 • 36 citations
Successful adoptive cellular immunotherapy is dependent on induction of a host immune response triggered by cytokine (IFN-gamma and granulocyte/macrophage colony-stimulating factor) producing donor tumor-infiltrating lymphocytes.
1998 • 36 citations
Reactivation of murine tumour-infiltrating lymphocytes with solid-phase anti-CD3 antibody: in vitro cytokine production is associated with in vivo efficacy
1994 • 35 citations
A novel role for autologous tumour cell vaccination in the immunotherapy of the poorly immunogenic B16-BL6 melanoma
1992 • 30 citations
Successful Adoptive Cellular Immunotherapy Is Dependent on Induction of a Host Immune Response Triggered by Cytokine (IFN-γ and Granulocyte/Macrophage Colony-Stimulating Factor) Producing Donor Tumor-Infiltrating Lymphocytes
1998 • 29 citations
Concurrent Induction of CD4+ and CD8+ T Cells During Tumor Growth with Antitumor Reactivity in Adoptive Immunotherapy
1997 • 11 citations